Naohito Nozaki
Overview
Explore the profile of Naohito Nozaki including associated specialties, affiliations and a list of published articles.
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Articles
47
Citations
2690
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Recent Articles
11.
Gallego-Paez L, Tanaka H, Bando M, Takahashi M, Nozaki N, Nakato R, et al.
Mol Biol Cell
. 2013 Nov;
25(2):302-17.
PMID: 24258023
The structural maintenance of chromosomes (SMC) proteins constitute the core of critical complexes involved in structural organization of chromosomes. In yeast, the Smc5/6 complex is known to mediate repair of...
12.
Sato Y, Mukai M, Ueda J, Muraki M, Stasevich T, Horikoshi N, et al.
Sci Rep
. 2013 Aug;
3:2436.
PMID: 23942372
Post-translational histone modifications play key roles in gene regulation, development, and differentiation, but their dynamics in living organisms remain almost completely unknown. To address this problem, we developed a genetically...
13.
Kajiwara A, Tsuchiya Y, Takata T, Nyunoya M, Nozaki N, Ihara H, et al.
Nitric Oxide
. 2013 Apr;
34:3-9.
PMID: 23624270
The purpose of this study was to investigate the roles of neuronal nitric oxide synthase (nNOS), Ca(2+)/calmodulin (CaM)-dependent protein kinases (CaMKs), and protein kinase C (PKC) in nicotine-induced extracellular signal-regulated...
14.
Nozawa R, Nagao K, Igami K, Shibata S, Shirai N, Nozaki N, et al.
Nat Struct Mol Biol
. 2013 Apr;
20(5):566-73.
PMID: 23542155
Human inactive X chromosome (Xi) forms a compact structure called the Barr body, which is enriched in repressive histone modifications such as trimethylation of histone H3 Lys9 (H3K9me3) and Lys27...
15.
Deardorff M, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, et al.
Nature
. 2012 Aug;
489(7415):313-7.
PMID: 22885700
Cornelia de Lange syndrome (CdLS) is a dominantly inherited congenital malformation disorder, caused by mutations in the cohesin-loading protein NIPBL for nearly 60% of individuals with classical CdLS, and by...
16.
Brookes E, de Santiago I, Hebenstreit D, Morris K, Carroll T, Xie S, et al.
Cell Stem Cell
. 2012 Feb;
10(2):157-70.
PMID: 22305566
Polycomb repressor complexes (PRCs) are important chromatin modifiers fundamentally implicated in pluripotency and cancer. Polycomb silencing in embryonic stem cells (ESCs) can be accompanied by active chromatin and primed RNA...
17.
Kokabu Y, Murayama Y, Kuwabara N, Oroguchi T, Hashimoto H, Tsutsui Y, et al.
J Biol Chem
. 2011 Oct;
286(50):43569-76.
PMID: 22033972
In eukaryotes, DNA strand exchange is the central reaction of homologous recombination, which is promoted by Rad51 recombinases forming a right-handed nucleoprotein filament on single-stranded DNA, also known as a...
18.
Sugiyama T, Chino M, Tsurimoto T, Nozaki N, Ishimi Y
J Biochem
. 2011 Oct;
151(2):129-37.
PMID: 22023799
The antibiotic heliquinomycin inhibited cellular DNA replication at IC(50) of 2.5 µM without affecting level of chromatin-bound MCM4 and without activating the DNA replication stress checkpoint system, suggesting that heliquinomycin...
19.
Ishikawa K, Ohsumi T, Tada S, Natsume R, Kundu L, Nozaki N, et al.
Genes Cells
. 2011 Sep;
16(10):1050-62.
PMID: 21895891
The nucleosome, which is composed of DNA wrapped around a histone octamer, is a fundamental unit of chromatin and is duplicated during the eukaryotic DNA replication process. The evolutionarily conserved...
20.
Fujimoto T, Hatano N, Nozaki N, Yurimoto S, Kobayashi R, Tokumitsu H
Biochem Biophys Res Commun
. 2011 Jun;
410(1):45-51.
PMID: 21640082
Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) phosphorylates and activates specific downstream protein kinases including CaMKI, CaMKIV and 5'-AMP-activated protein kinase. In order to examine the variety of CaMKK-mediated signaling pathways, we...