Nadejda M Tsankova
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Explore the profile of Nadejda M Tsankova including associated specialties, affiliations and a list of published articles.
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54
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1013
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Recent Articles
1.
Xue Y, Hou X, Zhong Y, Zhang Y, Du S, Kang D, et al.
Nat Commun
. 2025 Mar;
16(1):2198.
PMID: 40038251
Lipid nanoparticle (LNP)-mRNA vaccines have demonstrated protective capability in combating SARS-CoV-2. Their extensive deployment across the global population leads to the broad presence of T-cell immunity against the SARS-CoV-2 spike...
2.
Peter C, Agarwal A, Watanabe R, Kassim B, Wang X, Lambert T, et al.
Cell Rep Methods
. 2024 Dec;
4(12):100911.
PMID: 39631398
We apply a single-molecule chromatin fiber sequencing (Fiber-seq) protocol designed for amplification-free cell-type-specific mapping of the regulatory architecture at nucleosome resolution along extended ∼10-kb chromatin fibers to neuronal and non-neuronal...
3.
Ross J, Puigdelloses-Vallcorba M, Pinero G, Soni N, Thomason W, DeSisto J, et al.
Immunity
. 2024 Oct;
57(11):2669-2687.e6.
PMID: 39395421
Pediatric high-grade gliomas (pHGGs), including hemispheric pHGGs and diffuse midline gliomas (DMGs), harbor mutually exclusive tumor location-specific histone mutations. Using immunocompetent de novo mouse models of pHGGs, we demonstrated that...
4.
Richardson T, Walker J, Hambardzumyan D, Brem S, Hatanpaa K, Viapiano M, et al.
Acta Neuropathol
. 2024 Jul;
148(1):5.
PMID: 39012509
In recent years, the classification of adult-type diffuse gliomas has undergone a revolution, wherein specific molecular features now represent defining diagnostic criteria of IDH-wild-type glioblastomas, IDH-mutant astrocytomas, and IDH-mutant 1p/19q-codeleted...
5.
Pellerin D, Del Gobbo G, Couse M, Dolzhenko E, Nageshwaran S, Cheung W, et al.
Nat Genet
. 2024 Jun;
56(7):1366-1370.
PMID: 38937606
The factors driving or preventing pathological expansion of tandem repeats remain largely unknown. Here, we assessed the FGF14 (GAA)·(TTC) repeat locus in 2,530 individuals by long-read and Sanger sequencing and...
6.
Zhu K, Bendl J, Rahman S, Vicari J, Coleman C, Clarence T, et al.
Sci Adv
. 2023 Oct;
9(41):eadg3754.
PMID: 37824614
The cellular complexity of the human brain is established via dynamic changes in gene expression throughout development that is mediated, in part, by the spatiotemporal activity of cis-regulatory elements (CREs)....
7.
Chen Z, Giotti B, Kaluzova M, Vallcorba M, Rawat K, Price G, et al.
J Clin Invest
. 2023 Sep;
133(22).
PMID: 37733448
Monocytes and monocyte-derived macrophages (MDMs) from blood circulation infiltrate glioblastoma (GBM) and promote growth. Here, we show that PDGFB-driven GBM cells induce the expression of the potent proinflammatory cytokine IL-1β...
8.
Richardson T, Yokoda R, Rashidipour O, Vij M, Snuderl M, Brem S, et al.
Neurooncol Adv
. 2023 Aug;
5(1):vdad085.
PMID: 37554222
Background: Mutations in mismatch repair (MMR) genes (, , , and are associated with microsatellite instability and a hypermutator phenotype in numerous systemic cancers, and germline MMR mutations have been...
9.
Yokoda R, Cobb W, Yong R, Crary J, Viapiano M, Walker J, et al.
J Neuropathol Exp Neurol
. 2023 Aug;
82(10):845-852.
PMID: 37550258
Homozygous deletion of CDKN2A/B is currently considered a molecular signature for grade 4 in IDH-mutant astrocytomas, irrespective of tumor histomorphology. The 2021 WHO Classification of CNS Tumors does not currently...
10.
LaMarca E, Saito A, Plaza-Jennings A, Espeso-Gil S, Hellmich A, Fernando M, et al.
bioRxiv
. 2023 Jul;
PMID: 37503149
Here, we construct genome-scale maps for R-loops, three-stranded nucleic acid structures comprised of a DNA/RNA hybrid and a displaced single strand of DNA, in the proliferative and differentiated zones of...