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N R CHOWDHURY

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Articles 86
Citations 1326
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Recent Articles
11.
Sauter B, Parashar B, CHOWDHURY N, Kadakol A, Ilan Y, Singh H, et al.
Gastroenterology . 2000 Oct; 119(5):1348-57. PMID: 11054394
Background & Aims: In the quest for a recombinant viral vector for liver-directed gene therapy that would permit both prolonged and efficient transgene expression in quiescent hepatocytes in vivo and...
12.
Kadakol A, Ghosh S, Sappal B, Sharma G, Chowdhury J, CHOWDHURY N
Hum Mutat . 2000 Oct; 16(4):297-306. PMID: 11013440
Uridine-diphosphoglucuronate glucuronosyltransferases (UGTs) are a family of enzymes that conjugate various endogenous and exogenous compounds with glucuronic acid and facilitate their excretion in the bile. Bilirubin-UGT(1) (UGT1A1) is the only...
13.
Minami H, Tada K, CHOWDHURY N, Chowdhury J, Onji M
J Hepatol . 2000 Aug; 33(2):183-8. PMID: 10952235
Background/aims: Gene transfer using recombinant Moloney murine leukemia viruses (rMoMuLV) requires mitosis of the target cell. Previously, we and others have used partial hepatectomy for induction of hepatocellular proliferation for...
14.
Guha C, CHOWDHURY N, Chowdhury J
Hepatology . 2000 Aug; 32(2):440-1. PMID: 10915758
No abstract available.
15.
Guha C, CHOWDHURY N, Chowdhury J
J Hepatol . 2000 Jul; 32(6):1031-4. PMID: 10898325
No abstract available.
16.
Ilan Y, Weksler-Zangen S, Ben-Horin S, Diment J, Sauter B, Rabbani E, et al.
Am J Gastroenterol . 2000 Apr; 95(4):966-73. PMID: 10763946
Objective: Inflammatory bowel diseases (IBD) are immune-mediated disorders wherein an imbalance between proinflammatory (Th1) and antiinflammatory (Th2) cytokines is thought to play a role in the pathogenesis. The aim of...
17.
Ghosh S, Takahashi M, Thummala N, Parashar B, CHOWDHURY N, Chowdhury J
J Hepatol . 2000 Mar; 32(1 Suppl):238-52. PMID: 10728808
Although liver-directed gene therapy arrived later than gene therapy directed at bone marrow cells, intrinsic advantages of the liver as a target organ make it likely that gene therapy for...
18.
Nagler A, Pines M, Abadi U, Pappo O, Zeira M, Rabbani E, et al.
Hepatology . 2000 Mar; 31(3):641-8. PMID: 10706554
In chronic graft versus host disease (cGVHD), an immune attack by transplanted donor lymphocytes results in damage of host target organs. A disbalance between proinflammatory (Th1) and anti-inflammatory cytokines (Th2)...
19.
Kren B, Parashar B, Bandyopadhyay P, CHOWDHURY N, Chowdhury J, Steer C
Proc Natl Acad Sci U S A . 1999 Sep; 96(18):10349-54. PMID: 10468611
Crigler-Najjar syndrome type I is characterized by unconjugated hyperbilirubinemia resulting from an autosomal recessive inherited deficiency of hepatic UDP-glucuronosyltransferase (UGT) 1A1 activity. The enzyme is essential for glucuronidation and biliary...
20.
Ilan Y, Saito H, Thummala N, CHOWDHURY N
Semin Liver Dis . 1999 Jun; 19(1):49-59. PMID: 10349683
Recombinant adenoviruses can infect nondividing cells with high efficiency and are rapidly concentrated in the liver after systemic administration, making them attractive for use in liver-directed gene therapy. However, there...