N Leitinger
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Explore the profile of N Leitinger including associated specialties, affiliations and a list of published articles.
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24
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1263
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Recent Articles
1.
Kharel Y, Huang T, Dunnavant K, Foster D, Souza G, Nimchuk K, et al.
bioRxiv
. 2024 May;
PMID: 38746194
S1P (sphingosine 1-phosphate) receptor modulator (SRM) drugs interfere with lymphocyte trafficking by downregulating lymphocyte S1P receptors. While the immunosuppressive activity of SRM drugs has proved useful in treating autoimmune diseases...
2.
Huber J, Loffler M, Bilban M, Reimers M, Kadl A, Todoric J, et al.
Int J Obes (Lond)
. 2006 Nov;
31(6):1004-13.
PMID: 17130847
Objective: Obesity is associated with reduced insulin sensitivity and extensive reorganization of adipose tissue. As polyunsaturated fatty acids (PUFA) appear to inhibit diabetes development, we investigated PUFA effects on markers...
3.
Furnkranz A, Leitinger N
Curr Pharm Des
. 2004 Mar;
10(8):915-21.
PMID: 15032694
Increasing evidence points to the role of oxidized phospholipids as modulators of inflammatory processes. These modified phospholipids are derived from lipoproteins or cellular membranes and accumulate at sites of inflammation...
4.
Berliner J, Subbanagounder G, Leitinger N, Watson A, Vora D
Trends Cardiovasc Med
. 2001 Nov;
11(3-4):142-7.
PMID: 11686004
There is growing evidence for the accumulation of phospholipid oxidation products (some of which can also be formed enzymatically) in several chronic disease processes including atherosclerosis. There also is considerable...
5.
Yeh M, Leitinger N, de Martin R, Onai N, Matsushima K, Vora D, et al.
Arterioscler Thromb Vasc Biol
. 2001 Oct;
21(10):1585-91.
PMID: 11597930
Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (Ox-PAPC) upregulates a spectrum of inflammatory cytokines and adhesion molecules different from those induced by classic inflammatory mediators such as tumor necrosis factor-alpha (TNF-alpha) or lipopolysaccharide. Interestingly, Ox-PAPC...
6.
Stulnig T, Huber J, Leitinger N, Imre E, Angelisova P, Nowotny P, et al.
J Biol Chem
. 2001 Aug;
276(40):37335-40.
PMID: 11489905
Polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (20:5 (n-3)) inhibit T lymphocyte activation probably by displacing acylated signaling proteins from membrane lipid rafts. Under physiological conditions, saturated fatty acyl...
7.
Leitinger N, Huber J, Rizza C, Mechtcheriakova D, Bochkov V, Koshelnick Y, et al.
FASEB J
. 2001 May;
15(7):1254-6.
PMID: 11344105
No abstract available.
8.
Subbanagounder G, Leitinger N, Schwenke D, Wong J, Lee H, Rizza C, et al.
Arterioscler Thromb Vasc Biol
. 2000 Oct;
20(10):2248-54.
PMID: 11031211
We previously described 3 bioactive oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (PAPC) containing oxovaleroyl (POVPC), glutaroyl (PGPC), and epoxyisoprostane (PEIPC) groups at the sn-2 position that were increased in minimally modified/oxidized low...
9.
Rizza C, Leitinger N, Yue J, Fischer D, Wang D, SHIH P, et al.
Lab Invest
. 1999 Oct;
79(10):1227-35.
PMID: 10532586
Lysophosphatidic acid (LPA) is produced by a variety of activated cell types and acts as an intercellular mediator of processes associated with inflammation and repair including platelets aggregation, and smooth...
10.
Leitinger N, Tyner T, Oslund L, Rizza C, Subbanagounder G, Lee H, et al.
Proc Natl Acad Sci U S A
. 1999 Oct;
96(21):12010-5.
PMID: 10518567
We previously have demonstrated that oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (OxPAPC), a component of minimally modified low density lipoprotein (MM-LDL), activates endothelial cells to bind monocytes. 1-Palmitoyl-2- (5-oxovaleroyl)-sn-glycero-3-phosphorylcholine (POVPC) and 1- palmitoyl-2-glutaroyl-sn-glycero-3-phosphorylcholine (PGPC),...