N C Partridge
Overview
Explore the profile of N C Partridge including associated specialties, affiliations and a list of published articles.
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67
Citations
1041
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Recent Articles
1.
Saranya I, Akshaya R, Gomathi K, Mohanapriya R, He Z, Partridge N, et al.
Noncoding RNA Res
. 2023 Nov;
9(1):153-164.
PMID: 38035043
Transforming growth factor-beta1 (TGF-β1) stimulates matrix metalloproteinase-13 (, a bone-remodeling gene) expression, and this effect requires p300-mediated Runx2 (Runt-related transcription factor 2) acetylation in osteoblasts. p300 and Runx2 are transcriptional...
2.
Akshaya R, Rohini M, He Z, Partridge N, Selvamurugan N
Int J Biol Macromol
. 2022 Oct;
222(Pt B):1974-1982.
PMID: 36208811
TGF-β1 (transforming growth factor-beta1), a secreted polypeptide cytokine, stimulates ATF-3 (activating transcription factor-3) expression in a sustained and prolonged manner in human breast cancer cells (MDA-MB231), but not in normal...
3.
Arumugam B, Vishal M, Shreya S, Malavika D, Rajpriya V, He Z, et al.
Biochimie
. 2018 Dec;
158:43-52.
PMID: 30562548
Parathyroid hormone (PTH) acts as a regulator of calcium homeostasis and bone remodeling. Runx2, an essential transcription factor in bone, is required for osteoblast differentiation. Noncoding RNAs such as long...
4.
Vishal M, Vimalraj S, Ajeetha R, Gokulnath M, Keerthana R, He Z, et al.
J Cell Physiol
. 2016 May;
232(2):371-380.
PMID: 27192628
Mesenchymal stem cells (MSCs) are multipotent cells and their differentiation into the osteoblastic lineage is strictly controlled by several regulators, including microRNAs (miRNAs). Runx2 is a bone transcription factor required...
5.
Gokulnath M, Partridge N, Selvamurugan N
Tumour Biol
. 2014 Nov;
36(3):1923-31.
PMID: 25380580
Activating transcription factor (ATF-3) is a stress response gene and is induced by transforming growth factor beta 1 (TGF-β1) in breast cancer cells. In this study, we dissected the functional...
6.
Shimizu E, Tamasi J, Partridge N
J Dent Res
. 2011 Dec;
91(3):268-74.
PMID: 22180568
Bisphosphonates are therapeutic agents in the treatment of post-menopausal osteoporosis. Although they have been associated with delayed healing in injured tissues, inappropriate femoral fractures, and osteonecrosis of the jaw (ONJ),...
7.
Sukumar D, Partridge N, Wang X, Shapses S
J Clin Endocrinol Metab
. 2011 Apr;
96(6):1852-8.
PMID: 21508136
Context: Chronic high levels of PTH may be associated with up-regulation of proteases and cytokines. Monocyte chemoattractant protein-1 (MCP-1) is an inflammatory cytokine, produced predominantly by macrophages and endothelial cells,...
8.
Sahithi K, Swetha M, Prabaharan M, Moorthi A, Saranya N, Ramasamy K, et al.
J Biomed Nanotechnol
. 2011 Feb;
6(4):333-9.
PMID: 21323106
The bacterial infection is one of the major problems associated with implant and reconstructive surgery of bone. Hence, the aim of this study was to develop biomaterials having antibacterial activity...
9.
Sukumar D, Shapses S, Partridge N, Schneider S
Osteoporos Int
. 2008 Jul;
19(12):1805-6.
PMID: 18636216
No abstract available.
10.
Raggatt L, Jefcoat Jr S, Choudhury I, Williams S, Tiku M, Partridge N
Osteoarthritis Cartilage
. 2006 Mar;
14(7):680-9.
PMID: 16516501
Objective: Matrix metalloproteinase-13 (MMP-13) is an extracellular MMP that cleaves type II collagen, the major protein component of cartilage, with high specificity and has been implicated in the pathology of...