N C Partridge
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Explore the profile of N C Partridge including associated specialties, affiliations and a list of published articles.
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67
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1041
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Recent Articles
11.
Walling H, Raggatt L, Irvine D, Barmina O, Toledano J, Goldring M, et al.
Osteoarthritis Cartilage
. 2003 Nov;
11(12):854-63.
PMID: 14629961
Objective: Collagenase-3, a matrix metalloproteinase (MMP-13) that can degrade collagen II and aggrecan, is produced by osteoarthritic (OA) chondrocytes and may contribute to matrix destruction in this disease. Our laboratory...
12.
Swarthout J, Doggett T, Lemker J, Partridge N
J Biol Chem
. 2000 Dec;
276(10):7586-92.
PMID: 11108712
Parathyroid hormone (PTH) is known to have both catabolic and anabolic effects on bone. The dual functionality of PTH may stem from its ability to activate two signal transduction mechanisms:...
13.
Partridge N, Fiacco G, Walling H, Barmina O, Jeffrey J, Ruh M
Arch Biochem Biophys
. 2000 Nov;
382(2):182-8.
PMID: 11068867
Since estrogen is important in preventing osteoporosis in postmenopausal women and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is an estrogen antagonist in reproductive tissues, we investigated the effects of 17beta-estradiol (E2) and TCDD on...
14.
Selvamurugan N, Brown R, Partridge N
J Cell Biochem
. 2000 Sep;
79(2):182-90.
PMID: 10967546
Collagenase-3 expression in osteoblastic (UMR 106-01, ROS 17/2.8) and non-osteoblastic cell lines (BC1, NIH3T3) was examined. We observed that parathyroid hormone (PTH) induces collagenase-3 expression only in UMR cells but...
15.
Toledano J, Partridge N
Trends Endocrinol Metab
. 2000 Aug;
11(7):255-6.
PMID: 10920380
No abstract available.
16.
Tuckermann J, Pittois K, Partridge N, Merregaert J, Angel P
J Bone Miner Res
. 2000 Jul;
15(7):1257-65.
PMID: 10893674
Endochondral bone formation requires the action of cells of the chondrocytic and osteoblastic lineage, which undergo continuous differentiation during this process. To identify subpopulations of resting, proliferating, and hypertrophic chondrocytes...
17.
Selvamurugan N, Partridge N
Mol Cell Biol Res Commun
. 2000 Jul;
3(4):218-23.
PMID: 10891395
Matrix metalloproteinases (MMPs) are a family of secreted or transmembrane proteins that have been implicated in multiple physiological and pathological processes related to extracellular matrix turnover. Recent evidence strongly suggests...
18.
Winchester S, Selvamurugan N, DAlonzo R, Partridge N
J Biol Chem
. 2000 Apr;
275(30):23310-8.
PMID: 10779518
Collagenase-3 mRNA is initially detectable when osteoblasts cease proliferation, increasing during differentiation and mineralization. We showed that this developmental expression is due to an increase in collagenase-3 gene transcription. Mutation...
19.
Selvamurugan N, Pulumati M, Tyson D, Partridge N
J Biol Chem
. 2000 Feb;
275(7):5037-42.
PMID: 10671545
Previously we showed that the activator protein-1 site and the runt domain binding site in the collagenase-3 promoter act cooperatively in response to parathyroid hormone (PTH) in the rat osteoblastic...
20.
Zemlo T, Garrison H, Partridge N, Ley T
FASEB J
. 2000 Feb;
14(2):221-30.
PMID: 10657979
No abstract available.