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N Brouwer

Explore the profile of N Brouwer including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 640
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Recent Articles
1.
Dubbelaar M, Misrielal C, Bajramovic J, Burm S, Zuiderwijk-Sick E, Brouwer N, et al.
Brain Behav Immun Health . 2021 Sep; 15:100265. PMID: 34589771
Microglia are tissue-resident macrophages of the central nervous system (CNS), and important for CNS development and homeostasis. In the adult CNS, microglia monitor environmental changes and react to tissue damage,...
2.
Kracht L, Borggrewe M, Eskandar S, Brouwer N, Chuva de Sousa Lopes S, Laman J, et al.
Science . 2020 Aug; 369(6503):530-537. PMID: 32732419
Microglia, immune cells of the central nervous system (CNS), are important for tissue development and maintenance and are implicated in CNS disease, but we lack understanding of human fetal microglia...
3.
Hu S, Karasiev V, Recoules V, Nilson P, Brouwer N, Torrent M
Nat Commun . 2020 Apr; 11(1):1989. PMID: 32332785
Superdense plasmas widely exist in planetary interiors and astrophysical objects such as brown-dwarf cores and white dwarfs. How atoms behave under such extreme-density conditions is not yet well understood, even...
4.
van Vliet E, Winnips J, Brouwer N
CBE Life Sci Educ . 2015 Jun; 14(3). PMID: 26113628
In flipped-class pedagogy, students prepare themselves at home before lectures, often by watching short video clips of the course contents. The aim of this study was to investigate the effects...
5.
Schaafsma W, Zhang X, van Zomeren K, Jacobs S, Georgieva P, Wolf S, et al.
Brain Behav Immun . 2015 Apr; 48:205-21. PMID: 25843371
Microglia, the innate immune cells of the central nervous system (CNS), react to endotoxins like bacterial lipopolysaccharides (LPS) with a pronounced inflammatory response. To avoid excess damage to the CNS,...
6.
Vainchtein I, Vinet J, Brouwer N, Brendecke S, Biagini G, Biber K, et al.
Glia . 2014 Jun; 62(10):1724-35. PMID: 24953459
Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS) characterized by loss of myelin accompanied by infiltration of T-lymphocytes and monocytes. Although it has been...
7.
Vinet J, van Zwam M, Dijkstra I, Brouwer N, van Weering H, Watts A, et al.
Br J Pharmacol . 2012 Nov; 168(6):1375-87. PMID: 23121557
Background And Purpose: Induction of cellular migration is the primary effect of chemokine receptor activation. However, several chemokine receptor-like proteins bind chemokines without subsequent induction of intracellular signalling and chemotaxis....
8.
Frakking F, Brouwer N, Dolman K, van Woensel J, Caron H, Kuijpers T, et al.
Clin Exp Immunol . 2011 Apr; 165(1):51-9. PMID: 21488869
Deficiency of mannose-binding lectin (MBL) has been suggested to influence duration of febrile neutropenia and prognosis in paediatric oncology patients. However, there is no consensus on the definition of MBL...
9.
Frakking F, Brouwer N, van Eijkelenburg N, Merkus M, Kuijpers T, Offringa M, et al.
Clin Exp Immunol . 2007 Aug; 150(2):255-62. PMID: 17711490
We investigated whether deficiency of mannose-binding lectin (MBL), a component of innate immunity, is associated with neonatal pneumonia and sepsis during the first 72 h, i.e. early onset, and during...
10.
Laursen I, Houen G, Hojrup P, Brouwer N, Krogsoe L, Blou L, et al.
Vox Sang . 2007 Apr; 92(4):338-50. PMID: 17456158
Background And Objectives: Mannan-binding lectin (MBL) is an important component of the innate immune defence; it binds to carbohydrate structures on pathogenic micro-organisms resulting in complement activation and opsonization. Individuals...