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B J L Eggen

Explore the profile of B J L Eggen including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 464
Followers 0
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Recent Articles
1.
Weinstein J, Jayadev S, Liddelow S, Eggen B
Glia . 2024 Nov; 73(3):448-450. PMID: 39587765
No abstract available.
2.
Reitsema V, Schreuder L, Gerrits E, Eggen B, Goris M, Laman J, et al.
Geroscience . 2024 Sep; PMID: 39287878
Hospitalized elderly patients frequently suffer from delirium, especially in the context of sepsis-associated encephalopathy. Current treatments of delirium are merely symptomatic. Calorie restriction (CR) is both a promising strategy to...
3.
Mastenbroek L, Kooistra S, Eggen B, Prins J
Semin Immunopathol . 2024 Jul; 46(1-2):1. PMID: 38990389
Activation of the maternal immune system during gestation has been associated with an increased risk for neurodevelopmental disorders in the offspring, particularly schizophrenia and autism spectrum disorder. Microglia, the tissue-resident...
4.
Kuil L, Chauhan R, de Graaf B, Cheng W, Kakiailatu N, Lasabuda R, et al.
Biochim Biophys Acta Mol Basis Dis . 2023 Dec; 1870(3):166991. PMID: 38128843
Hirschsprung disease (HSCR) is a complex genetic disorder characterized by the absence of enteric nervous system (ENS) in the distal region of the intestine. Down Syndrome (DS) patients have a...
5.
Dubbelaar M, Misrielal C, Bajramovic J, Burm S, Zuiderwijk-Sick E, Brouwer N, et al.
Brain Behav Immun Health . 2021 Sep; 15:100265. PMID: 34589771
Microglia are tissue-resident macrophages of the central nervous system (CNS), and important for CNS development and homeostasis. In the adult CNS, microglia monitor environmental changes and react to tissue damage,...
6.
Kracht L, Borggrewe M, Eskandar S, Brouwer N, Chuva de Sousa Lopes S, Laman J, et al.
Science . 2020 Aug; 369(6503):530-537. PMID: 32732419
Microglia, immune cells of the central nervous system (CNS), are important for tissue development and maintenance and are implicated in CNS disease, but we lack understanding of human fetal microglia...
7.
Cogut V, Bruintjes J, Eggen B, van der Zee E, Henning R
Brain Behav Immun . 2017 Oct; 68:17-22. PMID: 29038037
Hibernators tolerate low metabolism, reduced cerebral blood flow and hypothermia during torpor without noticeable neuronal or synaptic dysfunction upon arousal. Previous studies found extensive changes in brain during torpor, including...
8.
Mattei D, Ivanov A, Ferrai C, Jordan P, Guneykaya D, Buonfiglioli A, et al.
Transl Psychiatry . 2017 May; 7(5):e1120. PMID: 28485733
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of developing psychiatric pathologies in later life. This link may be bridged by a defective microglial phenotype...
9.
Schaafsma W, Zhang X, van Zomeren K, Jacobs S, Georgieva P, Wolf S, et al.
Brain Behav Immun . 2015 Apr; 48:205-21. PMID: 25843371
Microglia, the innate immune cells of the central nervous system (CNS), react to endotoxins like bacterial lipopolysaccharides (LPS) with a pronounced inflammatory response. To avoid excess damage to the CNS,...
10.
Vainchtein I, Vinet J, Brouwer N, Brendecke S, Biagini G, Biber K, et al.
Glia . 2014 Jun; 62(10):1724-35. PMID: 24953459
Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS) characterized by loss of myelin accompanied by infiltration of T-lymphocytes and monocytes. Although it has been...