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Mythili Dileepan

Explore the profile of Mythili Dileepan including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 296
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Recent Articles
1.
Fish S, Halley C, Dileepan M, Hertzel A, Dickey D, Bernlohr D
Biochem Biophys Res Commun . 2025 Jan; 749:151346. PMID: 39855040
Adipose is a complex tissue comprised of adipocytes, immune cells, endothelial and progenitor stem cells. In humans, there are at least nine defined adipose depots, each containing variable numbers of...
2.
Verma V, Dileepan M, Huang Q, Phan T, Hu W, Ly H, et al.
PLoS Pathog . 2022 Sep; 18(9):e1010874. PMID: 36121891
Influenza A virus (IAV) infection causes acute respiratory disease with potential severe and deadly complications. Viral pathogenesis is not only due to the direct cytopathic effect of viral infections but...
3.
Murphy H, Sanchez S, Ahmed S, Rahman M, Di D, Dileepan M, et al.
Virulence . 2022 Jul; 13(1):1216-1220. PMID: 35799426
No abstract available.
4.
Di D, Dileepan M, Ahmed S, Liang Y, Ly H
Pathogens . 2021 Aug; 10(8). PMID: 34451501
The SARS-CoV-2 nucleocapsid protein (N) binds a single-stranded viral RNA genome to form a helical ribonucleoprotein complex that is packaged into virion particles. N is relatively conserved among coronaviruses and...
5.
Dileepan M, Di D, Huang Q, Ahmed S, Heinrich D, Ly H, et al.
Virulence . 2021 Jun; 12(1):1597-1609. PMID: 34125647
The COVID-19 pandemic caused by the coronavirus SARS-CoV-2 is continuing to spread globally. SARS-CoV-2 infections of feline and canine species have also been reported. However, it is not entirely clear...
6.
Rao S, Rastle-Simpson S, Dileepan M, Sriramarao P
Methods Mol Biol . 2020 Nov; 2223:217-236. PMID: 33226598
Cellular inflammation, with elevated levels of Th1/Th2 cytokines, airway mucus hypersecretion, and thickening of the airway smooth muscle, are characteristic features of the allergic lung. Assessment of pathophysiological changes in...
7.
Dileepan M, Ha S, Rastle-Simpson S, Ge X, Greenberg Y, Wijesinghe D, et al.
Exp Lung Res . 2020 Jun; 46(7):243-257. PMID: 32578458
Exposure to various allergens has been shown to increase expression of ORMDL3 in the lung in models of allergic asthma. Studies using genetically modified (transgenic or knock out) mice have...
8.
Guedes A, Dileepan M, Jude J, Deshpande D, Walseth T, Kannan M
Curr Opin Pharmacol . 2020 Jun; 51:29-33. PMID: 32480246
The worldwide socioeconomical burden associated with chronic respiratory diseases is substantial. Enzymes involved in the metabolism of nicotinamide adenine dinucleotide (NAD) are increasingly being implicated in chronic airway diseases. One...
9.
Dileepan M, Ge X, Bastan I, Greenberg Y, Liang Y, Sriramarao P, et al.
J Immunol . 2019 Dec; 204(3):682-693. PMID: 31871023
Eosinophilia is a hallmark of allergic airway inflammation (AAI). Identifying key molecules and specific signaling pathways that regulate eosinophilic inflammation is critical for development of novel therapeutics. Tropomycin receptor kinase...
10.
Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe D, Kumar N, Yang J, et al.
Front Pharmacol . 2019 Oct; 10:1118. PMID: 31611798
Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and anti-inflammatory roles in allergic airway inflammation (AAI) and asthma. Expression of COX-2...