P Sriramarao
Overview
Explore the profile of P Sriramarao including associated specialties, affiliations and a list of published articles.
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Articles
88
Citations
2033
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Recent Articles
1.
Rao S, Rastle-Simpson S, Dileepan M, Sriramarao P
Methods Mol Biol
. 2020 Nov;
2223:217-236.
PMID: 33226598
Cellular inflammation, with elevated levels of Th1/Th2 cytokines, airway mucus hypersecretion, and thickening of the airway smooth muscle, are characteristic features of the allergic lung. Assessment of pathophysiological changes in...
2.
Dileepan M, Ha S, Rastle-Simpson S, Ge X, Greenberg Y, Wijesinghe D, et al.
Exp Lung Res
. 2020 Jun;
46(7):243-257.
PMID: 32578458
Exposure to various allergens has been shown to increase expression of ORMDL3 in the lung in models of allergic asthma. Studies using genetically modified (transgenic or knock out) mice have...
3.
Dileepan M, Ge X, Bastan I, Greenberg Y, Liang Y, Sriramarao P, et al.
J Immunol
. 2019 Dec;
204(3):682-693.
PMID: 31871023
Eosinophilia is a hallmark of allergic airway inflammation (AAI). Identifying key molecules and specific signaling pathways that regulate eosinophilic inflammation is critical for development of novel therapeutics. Tropomycin receptor kinase...
4.
Dileepan M, Rastle-Simpson S, Greenberg Y, Wijesinghe D, Kumar N, Yang J, et al.
Front Pharmacol
. 2019 Oct;
10:1118.
PMID: 31611798
Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and anti-inflammatory roles in allergic airway inflammation (AAI) and asthma. Expression of COX-2...
5.
Bastan I, Rendahl A, Seelig D, Day M, Hall E, Rao S, et al.
J Vet Intern Med
. 2018 Oct;
32(6):1911-1917.
PMID: 30294803
Background: Accurate identification of eosinophils in the gastrointestinal (GI) tract of dogs with eosinophilic GI disease (EGID) by histological evaluation is challenging. The currently used hematoxylin and eosin (H&E) staining...
6.
Al-Obaidi N, Mohan S, Liang S, Zhao Z, Nayak B, Li B, et al.
FASEB J
. 2018 Jul;
33(1):373-387.
PMID: 29975570
Chronic exposure of tubular renal cells to high glucose contributes to tubulointerstitial changes in diabetic nephropathy. In the present study, we identified a new fibrosis gene called galectin-1 (Gal-1), which...
7.
Ge X, Bastan I, Dileepan M, Greenberg Y, Ha S, Steen K, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Apr;
315(2):L227-L240.
PMID: 29696987
Fatty acid binding protein 4 (FABP4), a member of a family of lipid-binding proteins, is known to play a role in inflammation by virtue of its ability to regulate intracellular...
8.
Ge X, Bastan I, Ha S, Greenberg Y, Esko J, Rao S, et al.
Exp Lung Res
. 2018 Apr;
44(2):98-112.
PMID: 29621420
Background: HSPGs are glycoproteins containing covalently attached heparan sulfate (HS) chains which bind to growth factors, chemokines, etc., and regulate various aspects of inflammation including cell recruitment. We previously showed...
9.
Ha S, Dileepan M, Ge X, Kang B, Greenberg Y, Rao A, et al.
J Allergy Clin Immunol
. 2018 Mar;
142(6):1808-1817.e3.
PMID: 29522849
Background: Altered epithelial physical and functional barrier properties along with T1/T2 immune dysregulation are features of allergic asthma. Regulation of junction proteins to improve barrier function of airway epithelial cells...
10.
Bastan I, Ge X, Dileepan M, Greenberg Y, Guedes A, Hwang S, et al.
J Leukoc Biol
. 2018 Jan;
104(1):109-122.
PMID: 29345370
Prevalence of food allergies in the United States is on the rise. Eosinophils are recruited to the intestinal mucosa in substantial numbers in food allergen-driven gastrointestinal (GI) inflammation. Soluble epoxide...