Muthu K Shanmugam
Overview
Explore the profile of Muthu K Shanmugam including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
103
Citations
5218
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Glaviano A, Lau H, Carter L, Lee E, Lam H, Okina E, et al.
J Hematol Oncol
. 2025 Jan;
18(1):6.
PMID: 39806516
The tumor microenvironment (TME) is integral to cancer progression, impacting metastasis and treatment response. It consists of diverse cell types, extracellular matrix components, and signaling molecules that interact to promote...
2.
Zhu Y, Ackers-Johnson M, Shanmugam M, Pakkiri L, Drum C, Chen Y, et al.
Circulation
. 2024 Apr;
149(23):1833-1851.
PMID: 38586957
Background: Adult mammalian cardiomyocytes have limited proliferative capacity, but in specifically induced contexts they traverse through cell-cycle reentry, offering the potential for heart regeneration. Endogenous cardiomyocyte proliferation is preceded by...
3.
Mohan C, Shanmugam M, Gowda S, Chinnathambi A, Rangappa K, Sethi G
Phytomedicine
. 2024 Mar;
128:155379.
PMID: 38503157
Background: c-MET is a receptor tyrosine kinase which is classically activated by HGF to activate its downstream signaling cascades such as MAPK, PI3K/Akt/mTOR, and STAT3. The c-MET modulates cell proliferation,...
4.
Jung Y, Kim C, Shanmugam M, Deivasigamani A, Chinnathambi A, Alharbi S, et al.
Cell Signal
. 2023 Dec;
114:111003.
PMID: 38048857
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that directs the transcription of genes involved in the promotion of cell survival and proliferation, inflammation, angiogenesis, invasion,...
5.
Gupta N, Mohan C, Shanmugam M, Jung Y, Chinnathambi A, Alharbi S, et al.
Environ Res
. 2023 Jun;
232:116335.
PMID: 37290620
Environmental factors such as exposure to ionizing radiations, certain environmental pollutants, and toxic chemicals are considered as risk factors in the development of breast cancer. Triple-negative breast cancer (TNBC) is...
6.
Ang H, Mohan C, Shanmugam M, Leong H, Makvandi P, Rangappa K, et al.
Med Res Rev
. 2023 Mar;
43(4):1141-1200.
PMID: 36929669
Epithelial-mesenchymal transition (EMT) is a complex process with a primordial role in cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal phenotype. This transformation plays a pivotal role...
7.
Deveshegowda S, Metri P, Shivakumar R, Yang J, Rangappa S, Swamynayaka A, et al.
Molecules
. 2022 May;
27(9).
PMID: 35566199
A number of uracil amides cleave poly (ADP-ribose) polymerase and therefore novel thiouracil amide compounds were synthesized and screened for the loss of cell viability in a human-estrogen-receptor-positive breast cancer...
8.
Cui J, Yuan Y, Shanmugam M, Anbalagan D, Tan T, Sethi G, et al.
Int J Biol Sci
. 2021 Nov;
17(15):4254-4270.
PMID: 34803496
MicroRNAs (miRNAs) are endogenous ~22nt RNAs that play critical regulatory roles in various biological and pathological processes, including various cancers. Their function in renal cancer has not been fully elucidated....
9.
Sajith A, Narasimhamurthy K, Shanmugam M, Rangappa S, Nayak S, Chinnathambi A, et al.
Bioorg Med Chem Lett
. 2021 Aug;
50:128332.
PMID: 34418571
Signal transducer and activator of transcription 3 (STAT3) is a tumorigenic transcription factor that is persistently activated in various human cancers including hepatocellular carcinoma (HCC). Therefore, STAT3 is considered as...
10.
Sikka S, Shanmugam M, Siveen K, Ong T, Yang M, Lee J, et al.
Eur J Pharmacol
. 2021 Jun;
906:174274.
PMID: 34146587
Prostate cancer (PCa) is a common disease among men especially in the old age. The deregulated activation of oncogenic and pro-survival transcription factors has been linked with tumor progression in...