Kanchugarakoppal S Rangappa
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Explore the profile of Kanchugarakoppal S Rangappa including associated specialties, affiliations and a list of published articles.
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148
Citations
1731
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Recent Articles
1.
Kim N, Vishwanath D, Basappa S, Kumar Harish K, Madegowda M, Rangappa K, et al.
Chem Biol Interact
. 2024 Oct;
404:111285.
PMID: 39442680
β-catenin is frequently implicated in signaling pathways that regulate autophagy, and the production of reactive oxygen species (ROS) has been linked to autophagy activation. Isoxazole-based nucleoside compounds have demonstrated anti-cancer...
2.
V S, N P, Kachigere B H, D C V, Gowda D, B S C, et al.
Heliyon
. 2024 Oct;
10(19):e38105.
PMID: 39386832
A series of novel N,2-diphenyl-6-(aryl/heteroaryl)quinoline-4-carboxamide derivatives were designed and synthesized using the Suzuki coupling reaction and evaluated them for their anticancer activity. These compounds were screened for anti-colon cancer activity...
3.
Yuan J, Yang L, Li Z, Zhang H, Wang Q, Wang B, et al.
IUBMB Life
. 2024 Sep;
76(12):1309-1324.
PMID: 39275910
Several chemotherapeutics against breast cancer are constrained by their adverse effects and chemoresistance. The development of novel chemotherapeutics to target metastatic breast cancer can bring effective clinical outcomes. Many breast...
4.
Gowda S, Kim N, Harsha K, Gowda D, Suresh R, Deivasigamani A, et al.
J Adv Res
. 2024 Aug;
PMID: 39216686
Introduction: Hepatocellular carcinoma (HCC) is a fatal cancer that is often diagnosed at the advanced stages which limits the available therapeutic options. The interaction of HGF with c-MET (a receptor...
5.
Jung Y, Suresh R, Mohan C, Harsha K, Shivakumara C, Rangappa K, et al.
Biochimie
. 2024 Aug;
227(Pt A):262-272.
PMID: 39098374
MAPK pathway regulates the major events including cell division, cell death, migration, invasion, and angiogenesis. Small molecules that modulate the MAPK pathway have been demonstrated to impart cytotoxicity in cancer...
6.
Yang M, Basappa B, Deveshegowda S, Ravish A, Mohan A, Nagaraja O, et al.
J Adv Res
. 2024 Jul;
PMID: 39067696
Introduction: Globally, colorectal cancer (CRC) is the third most common type of cancer, and its treatment frequently includes the utilization of drugs based on antibodies and small molecules. The development...
7.
Suresh R, Jung Y, Harsha K, Mohan C, Ahn K, Rangappa K
Chem Biol Interact
. 2024 Jul;
399:111143.
PMID: 39004389
Deregulated activation of the Wnt/β-catenin pathway is observed in many types of human malignancies including colon cancer. Abrogation of the Wnt/β-catenin pathway has been demonstrated as an effective way of...
8.
Mohan C, Rangappa K, Sethi G
MedComm (2020)
. 2024 Mar;
5(4):e492.
PMID: 38532948
In wild-type cells, TMEM25 physically associates with EGFR monomer and suppresses the EGFR-mediated STAT3 phosphorylation, which results in the sequestration of unphosphorylated STAT3 in the cytoplasm. In TMEM cells, EGFR...
9.
Mohan C, Shanmugam M, Gowda S, Chinnathambi A, Rangappa K, Sethi G
Phytomedicine
. 2024 Mar;
128:155379.
PMID: 38503157
Background: c-MET is a receptor tyrosine kinase which is classically activated by HGF to activate its downstream signaling cascades such as MAPK, PI3K/Akt/mTOR, and STAT3. The c-MET modulates cell proliferation,...
10.
Verma S, Rangappa S, Verma R, Xue F, Verma S, Sharath Kumar K, et al.
Bioorg Chem
. 2024 Mar;
145:107241.
PMID: 38437761
The discovery of new small molecule-based inhibitors is an attractive field in medicinal chemistry. Structurally diversified heterocyclic derivatives have been investigated to combat multi-drug resistant bacterial infections and they offers...