Murli Dhar Kharya
Overview
Explore the profile of Murli Dhar Kharya including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
56
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Jain P, Khurana N, Pounikar Y, Gajbhiye A, Kharya M
J Liposome Res
. 2013 Mar;
23(2):110-8.
PMID: 23506220
Andrographis paniculata is a medicinal herb used extensively for various ailments and contains therapeutically active phytoconstituent, andrographolide (AN). Although hepatoprotective activity of AN is established, but their bioavailability is restricted...
2.
Rajak H, Singh Thakur B, Singh A, Raghuvanshi K, Sah A, Veerasamy R, et al.
Bioorg Med Chem Lett
. 2012 Dec;
23(3):864-8.
PMID: 23265873
Two novel series of N(4)-(5-(2/3/4-substituted-phenyl)-1,3,4-oxadiazol-2-yl)-N(1)-(2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enylidene)semicarbazide and N(4)-(5-(2/3/4-substituted-phenyl)-1,3,4-oxadiazol-2-yl)-N(1)-(3,7-dimethylocta-3,6-dienylidene)-semicarbazide were synthesized to meet structural prerequisite indispensable for anticonvulsant activity. The anticonvulsant activities of the compounds were investigated using maximal electroshock seizure (MES),...
3.
Chaurasia A, Kharya M, Sharma B, Roy P
J Complement Integr Med
. 2012 Sep;
9:Article 21.
PMID: 22944716
Exposure of rampant higher glucose level in diabetic condition could lead earlier and late diabetic complication eventually caused malign effect in body organs. The aim of the present work was...
4.
Rajak H, Thakur B, Kumar P, Parmar P, Chander Sharma P, Veerasamy R, et al.
Acta Pol Pharm
. 2012 May;
69(2):253-61.
PMID: 22568039
The incomplete seizure control with frequent adverse effects of current anticonvulsant drugs and the importance of semicarbazones, quinazolines and 2,5-disubstituted 1,3,4-thiadiazoles as anticonvulsant pharmacophore prompted us to carry out synthesis...
5.
Rajak H, Agarawal A, Parmar P, Singh Thakur B, Veerasamy R, Chander Sharma P, et al.
Bioorg Med Chem Lett
. 2011 Aug;
21(19):5735-8.
PMID: 21875796
The enzymatic inhibition of histone deacetylase activity has come out as a novel and effectual means for the treatment of cancer. Two novel series of 2-[5-(4-substitutedphenyl)-[1,3,4]-oxadiazol/thiadiazol-2-ylamino]-pyrimidine-5-carboxylic acid (tetrahydro-pyran-2-yloxy)-amides were designed...
6.
Rajak H, Singour P, Kharya M, Mishra P
Chem Biol Drug Des
. 2011 Jan;
77(2):152-8.
PMID: 21266018
In search for a better anticonvulsant drug and the importance of semicarbazones and 2,5-disubstituted 1,3,4-oxadiazoles as anticonvulsant pharmacophore, a series of novel substituted semicarbazones were designed, synthesized, and evaluated for...
7.
Rajak H, Behera C, Pawar R, Singour P, Kharya M
Acta Pol Pharm
. 2010 Sep;
67(5):503-10.
PMID: 20873418
A novel series of N'-{5-[(1H-indol-3-ylmethyl)-1,3,4-thiadiazol-2-yl}-N4-(4-substituted benzaldehyde)-semicarbazones, N1-{5-[(1H-indol-3-ylmethyl)-1,3,4-thiadiazol-2-yl}-N4-[1-(4-substituted phenyl)ethanone]-semicarbazones and N1-{5-[(1H-indol-3-ylmethyl)-1,3,4-thiadiazol-2-yl}-N4-[1-(4-substituted phenyl) (phenyl) methanone]-semicarbazones were synthesized and evaluated for their anticonvulsant potential using maximal electroshock seizure (MES) and subcutaneous pentylenetrtrazole (scPFZ)...
8.
Rajak H, Deshmukh R, Veerasamy R, Sharma A, Mishra P, Kharya M
Bioorg Med Chem Lett
. 2010 Jun;
20(14):4168-72.
PMID: 20558061
A series of novel N(1)-{5-[(naphthalene-2-yloxy)methyl]-1,3,4-oxadiazol-2-yl}-N(4)-(4-substitutedbenzaldehyde)-semicarbazone, N(1)-{5-[(naphthalene-2-yloxy)methyl]-1,3,4-oxadiazol-2-yl}-N(4)-[1-(4-substitutedphenyl)ethanone]-semicarbazone and N(1)-{5-[(naphthalene-2-yloxy)methyl]-1,3,4-oxadiazol-2-yl}-N(4)-[1-(4-substitutedphenyl) (phenyl) methanone]-semicarbazone were designed and synthesized on the basis of semicarbazone based pharmacophoric model to meet the structural requirements necessary for anticonvulsant...
9.
Rajak H, Deshmukh R, Aggarwal N, Kashaw S, Kharya M, Mishra P
Arch Pharm (Weinheim)
. 2009 Jul;
342(8):453-61.
PMID: 19565600
A series of novel N(1)-[5-(4-substituted phenyl)-1,3,4-thiadiazol-2-yl]-N(4)-(4-substituted benzaldehyde)-semicarbazone 1-12, N(1)-[5-(4-substituted phenyl)-1,3,4-thiadiazol-2-yl]-N(4)-[1-(4-substituted phenyl)ethanone]-semicarbazone 13-16, and N(1)-[5-(4-substituted phenyl)-1,3,4-thiadiazol-2-yl]-N(4)-[1-(4-substituted phenyl) (phenyl) methanone]-semicarbazone 17-20 were synthesized for their anticonvulsant activity. The chemical structures of the...
10.
Rajak H, Kharya M, Mishra P
Arch Pharm (Weinheim)
. 2008 Feb;
341(4):247-61.
PMID: 18293435
A novel series of acetamides carrying substituted-1,3,4-oxadiazole moiety were synthesized from reaction of 5-aryl-2-chloroacetamido-1,3,4-oxadiazoles with different secondary amines. The local anesthetic potential of the compounds was investigated using rabbit corneal...