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Bhupendra Singh Thakur

Explore the profile of Bhupendra Singh Thakur including associated specialties, affiliations and a list of published articles. Areas
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Citations 25
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Recent Articles
1.
Rajak H, Singh Thakur B, Singh A, Raghuvanshi K, Sah A, Veerasamy R, et al.
Bioorg Med Chem Lett . 2012 Dec; 23(3):864-8. PMID: 23265873
Two novel series of N(4)-(5-(2/3/4-substituted-phenyl)-1,3,4-oxadiazol-2-yl)-N(1)-(2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enylidene)semicarbazide and N(4)-(5-(2/3/4-substituted-phenyl)-1,3,4-oxadiazol-2-yl)-N(1)-(3,7-dimethylocta-3,6-dienylidene)-semicarbazide were synthesized to meet structural prerequisite indispensable for anticonvulsant activity. The anticonvulsant activities of the compounds were investigated using maximal electroshock seizure (MES),...
2.
Rajak H, Kumar P, Parmar P, Singh Thakur B, Veerasamy R, Chander Sharma P, et al.
Eur J Med Chem . 2012 May; 53:390-7. PMID: 22541394
Histone deacetylase inhibitors have been actively explored as a new generation of chemotherapeutics for cancers, generally known as epigenetic therapeutics. Two novel series of N-(2-amino-phenyl)-4-{[(2/3/4-substituted-phenylcarbamoyl)-methyl]-amino}-butyramide and N-(2-amino-phenyl)-4-{[(2/3/4-substituted-phenylcarbamoyl)-methyl]-amino}benzamide were designed and...
3.
Rajak H, Agarawal A, Parmar P, Singh Thakur B, Veerasamy R, Chander Sharma P, et al.
Bioorg Med Chem Lett . 2011 Aug; 21(19):5735-8. PMID: 21875796
The enzymatic inhibition of histone deacetylase activity has come out as a novel and effectual means for the treatment of cancer. Two novel series of 2-[5-(4-substitutedphenyl)-[1,3,4]-oxadiazol/thiadiazol-2-ylamino]-pyrimidine-5-carboxylic acid (tetrahydro-pyran-2-yloxy)-amides were designed...