Moritz Gerstung
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Explore the profile of Moritz Gerstung including associated specialties, affiliations and a list of published articles.
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80
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12386
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Recent Articles
1.
Ritter M, Blume C, Tang Y, Patel A, Patel B, Berghaus N, et al.
Nat Cancer
. 2025 Jan;
6(2):292-306.
PMID: 39880907
The diagnostic landscape of brain tumors integrates comprehensive molecular markers alongside traditional histopathological evaluation. DNA methylation and next-generation sequencing (NGS) have become a cornerstone in central nervous system (CNS) tumor...
2.
Panten J, Del Prete S, Cleland J, Saunders L, van Riet J, Schneider A, et al.
Nat Commun
. 2024 Oct;
15(1):8814.
PMID: 39394207
The Four Core Genotypes (FCG) is a mouse model system used to disentangle the function of sex chromosomes and hormones. We report that a copy of a 3.2 MB region...
3.
Herms A, Fernandez-Antoran D, Alcolea M, Kalogeropoulou A, Banerjee U, Piedrafita G, et al.
Nat Genet
. 2024 Sep;
56(10):2158-2173.
PMID: 39313617
Aging epithelia are colonized by somatic mutations, which are subjected to selection influenced by intrinsic and extrinsic factors. The lack of suitable culture systems has slowed the study of this...
4.
Gerstung M, Liu D, Ghassemi M, Zou J, Chowell D, Teuwen J, et al.
Cancer Cell
. 2024 Jun;
42(6):915-918.
PMID: 38861926
Experts discuss the challenges and opportunities of using artificial intelligence (AI) to study the evolution of cancer cells and their microenvironment, improve diagnosis, predict treatment response, and ensure responsible implementation...
5.
Jung A, Holm P, Gaurav K, Hjaltelin J, Placido D, Mortensen L, et al.
Lancet Digit Health
. 2024 May;
6(6):e396-e406.
PMID: 38789140
Background: Health care is experiencing a drive towards digitisation, and many countries are implementing national health data resources. Although a range of cancer risk models exists, the utility on a...
6.
De Zuani M, Xue H, Park J, Dentro S, Seferbekova Z, Tessier J, et al.
Nat Commun
. 2024 May;
15(1):4388.
PMID: 38782901
Lung cancer is the second most frequently diagnosed cancer and the leading cause of cancer-related mortality worldwide. Tumour ecosystems feature diverse immune cell types. Myeloid cells, in particular, are prevalent...
7.
Jin D, Liang S, Shmatko A, Arnold A, Horst D, Grunewald T, et al.
Nat Commun
. 2024 Apr;
15(1):3063.
PMID: 38594278
Programmed cell death ligand 1 (PDL1), as an important biomarker, is quantified by immunohistochemistry (IHC) with few established histopathological patterns. Deep learning aids in histopathological assessment, yet heterogeneity and lacking...
8.
Marconato L, Palla G, Yamauchi K, Virshup I, Heidari E, Treis T, et al.
Nat Methods
. 2024 Mar;
22(1):58-62.
PMID: 38509327
Spatially resolved omics technologies are transforming our understanding of biological tissues. However, the handling of uni- and multimodal spatial omics datasets remains a challenge owing to large data volumes, heterogeneity...
9.
Gu M, Kovilakam S, Dunn W, Marando L, Barcena C, Mohorianu I, et al.
Nat Genet
. 2023 Sep;
55(10):1777.
PMID: 37726541
No abstract available.
10.
Gu M, Kovilakam S, Dunn W, Marando L, Barcena C, Mohorianu I, et al.
Nat Genet
. 2023 Aug;
55(9):1523-1530.
PMID: 37620601
The myeloid neoplasms encompass acute myeloid leukemia, myelodysplastic syndromes and myeloproliferative neoplasms. Most cases arise from the shared ancestor of clonal hematopoiesis (CH). Here we analyze data from 454,340 UK...