Moritz Gerstung
Overview
Explore the profile of Moritz Gerstung including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
80
Citations
12386
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Almeida J, Gudgin E, Besser M, Dunn W, Cooper J, Haferlach T, et al.
Nat Commun
. 2023 Jul;
14(1):4378.
PMID: 37474506
Many hematological diseases are characterized by altered abundance and morphology of blood cells and their progenitors. Myelodysplastic syndromes (MDS), for example, are a group of blood cancers characterised by cytopenias,...
12.
Gerstung M, Jolly C, Leshchiner I, Dentro S, Gonzalez S, Rosebrock D, et al.
Nature
. 2023 Jan;
614(7948):E42.
PMID: 36697833
No abstract available.
13.
Abby E, Dentro S, Hall M, Fowler J, Ong S, Sood R, et al.
Nat Genet
. 2023 Jan;
55(2):232-245.
PMID: 36658434
NOTCH1 mutant clones occupy the majority of normal human esophagus by middle age but are comparatively rare in esophageal cancers, suggesting NOTCH1 mutations drive clonal expansion but impede carcinogenesis. Here...
14.
Light N, Layeghifard M, Attery A, Subasri V, Zatzman M, Anderson N, et al.
Nat Commun
. 2023 Jan;
14(1):77.
PMID: 36604421
Li-Fraumeni syndrome (LFS) is a hereditary cancer predisposition syndrome associated with germline TP53 pathogenic variants. Here, we perform whole-genome sequence (WGS) analysis of tumors from 22 patients with TP53 germline...
15.
Seferbekova Z, Lomakin A, Yates L, Gerstung M
Nat Rev Genet
. 2022 Dec;
24(5):295-313.
PMID: 36494509
The natural history of cancers can be understood through the lens of evolution given that the driving forces of cancer development are mutation and selection of fitter clones. Cancer growth...
16.
Lomakin A, Svedlund J, Strell C, Gataric M, Shmatko A, Rukhovich G, et al.
Nature
. 2022 Nov;
611(7936):594-602.
PMID: 36352222
Genome sequencing of cancers often reveals mosaics of different subclones present in the same tumour. Although these are believed to arise according to the principles of somatic evolution, the exact...
17.
Murai K, Dentro S, Ong S, Sood R, Fernandez-Antoran D, Herms A, et al.
Nat Commun
. 2022 Oct;
13(1):6206.
PMID: 36266286
Aging normal human oesophagus accumulates TP53 mutant clones. These are the origin of most oesophageal squamous carcinomas, in which biallelic TP53 disruption is almost universal. However, how p53 mutant clones...
18.
Shmatko A, Laleh N, Gerstung M, Kather J
Nat Cancer
. 2022 Sep;
3(9):1026-1038.
PMID: 36138135
Artificial intelligence (AI) methods have multiplied our capabilities to extract quantitative information from digital histopathology images. AI is expected to reduce workload for human experts, improve the objectivity and consistency...
19.
Vohringer H, Sanderson T, Sinnott M, De Maio N, Nguyen T, Goater R, et al.
Nature
. 2022 Jun;
606(7915):E18.
PMID: 35701578
No abstract available.
20.
Fabre M, Almeida J, Fiorillo E, Mitchell E, Damaskou A, Rak J, et al.
Nature
. 2022 Jun;
606(7913):335-342.
PMID: 35650444
Clonal expansions driven by somatic mutations become pervasive across human tissues with age, including in the haematopoietic system, where the phenomenon is termed clonal haematopoiesis. The understanding of how and...