Morag H Stewart
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Explore the profile of Morag H Stewart including associated specialties, affiliations and a list of published articles.
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11
Citations
684
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Recent Articles
1.
Burberry A, Suzuki N, Wang J, Moccia R, Mordes D, Stewart M, et al.
Sci Transl Med
. 2016 Jul;
8(347):347ra93.
PMID: 27412785
C9ORF72 mutations are found in a significant fraction of patients suffering from amyotrophic lateral sclerosis and frontotemporal dementia, yet the function of the C9ORF72 gene product remains poorly understood. We...
2.
Stewart M, Albert M, Sroczynska P, Cruickshank V, Guo Y, Rossi D, et al.
Blood
. 2015 Feb;
125(13):2075-8.
PMID: 25655602
Jarid1b/KDM5b is a histone demethylase that regulates self-renewal and differentiation in stem cells and cancer; however, its function in hematopoiesis is unclear. Here, we find that Jarid1b is highly expressed...
3.
Stewart M, Gutierrez-Martinez P, Beerman I, Garrison B, Gallagher E, LeRoith D, et al.
Blood
. 2014 Oct;
124(20):3076-80.
PMID: 25274507
Growth hormone receptor (Ghr) signaling is important in a wide variety of cellular processes including aging; however, the role of Ghr signaling in hematopoietic stem cell (HSC) biology remains unexplored....
4.
Stewart M
Curr Drug Deliv
. 2013 Mar;
11(5):592-604.
PMID: 23517625
Pluripotent stem cell research has developed over the last fifty years from the study of embryonic development to a multifaceted discipline that encompasses development, epigenetics, reprogramming, cell therapy, disease modeling...
5.
Stewart M, Bendall S, Levadoux-Martin M, Bhatia M
Nat Methods
. 2010 Oct;
7(11):917-22.
PMID: 20953174
Human embryonic stem cells (hESCs) have unique self-renewal and differentiation properties, which are experimentally measured using functional assays. hESC cultures are known to be heterogeneous, but whether subsets of cells...
6.
Bendall S, Hughes C, Campbell J, Stewart M, Pittock P, Liu S, et al.
Mol Cell Proteomics
. 2008 Oct;
8(3):421-32.
PMID: 18936058
The derivation and long-term maintenance of human embryonic stem cells (hESCs) has been established in culture formats that are both dependent and independent of support (feeder) cells. However, the factors...
7.
Deconstructing human embryonic stem cell cultures: niche regulation of self-renewal and pluripotency
Stewart M, Bendall S, Bhatia M
J Mol Med (Berl)
. 2008 Jun;
86(8):875-86.
PMID: 18521556
The factors and signaling pathways controlling pluripotent human cell properties, both embryonic and induced, have not been fully investigated. Failure to account for functional heterogeneity within human embryonic stem cell...
8.
Bendall S, Hughes C, Stewart M, Doble B, Bhatia M, Lajoie G
Mol Cell Proteomics
. 2008 May;
7(9):1587-97.
PMID: 18487603
Recent studies using stable isotope labeling with amino acids in culture (SILAC) in quantitative proteomics have made mention of the problematic conversion of isotope-coded arginine to proline in cells. The...
9.
Bendall S, Stewart M, Bhatia M
Regen Med
. 2008 May;
3(3):365-76.
PMID: 18462059
In vivo the stem cell niche is an essential component in controlling and maintaining the stem cells' ability to survive and respond to injury. Human embryonic stem cells (hESCs) appear...
10.
Bendall S, Stewart M, Menendez P, George D, Vijayaragavan K, Werbowetski-Ogilvie T, et al.
Nature
. 2007 Jul;
448(7157):1015-21.
PMID: 17625568
Distinctive properties of stem cells are not autonomously achieved, and recent evidence points to a level of external control from the microenvironment. Here, we demonstrate that self-renewal and pluripotent properties...