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Monika Malm-Erjefalt

Explore the profile of Monika Malm-Erjefalt including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 107
Followers 0
Related Specialties
Pharmacology
Cell Biology
Molecular Biology
Top 10 Co-Authors
Jonas S Erjefalt
Carl G A Persson
Milan Zdravkovic
Per-Olof Ericsson
Uffe Larsen
Jan Jaap Van Lier
Hans Lennernas
Hans Helleberg
Berend Oosterhuis
Timothy J Williams
Published In
Am J Respir Cell Mol Biol
Int Arch Allergy Immunol
J Immunol Methods
Drug Metab Dispos
J Ocul Pharmacol Ther
Affiliations
Soon will be listed here.
Recent Articles
1.
Effect on the Gastrointestinal Absorption of Drugs from Different Classes in the Biopharmaceutics Classification System, When Treating with Liraglutide
Malm-Erjefalt M, Ekblom M, Vouis J, Zdravkovic M, Lennernas H
Mol Pharm . 2015 Oct; 12(11):4166-73. PMID: 26426736
Like other GLP-1 receptor agonists used for treatment of type 2 diabetes, liraglutide delays gastric emptying. In this clinical absorption study, the primary objective was to investigate the effect of...
2.
Metabolism and excretion of the once-daily human glucagon-like peptide-1 analog liraglutide in healthy male subjects and its in vitro degradation by dipeptidyl peptidase IV and neutral endopeptidase
Malm-Erjefalt M, Bjornsdottir I, Vanggaard J, Helleberg H, Larsen U, Oosterhuis B, et al.
Drug Metab Dispos . 2010 Aug; 38(11):1944-53. PMID: 20709939
Liraglutide is a novel once-daily human glucagon-like peptide (GLP)-1 analog in clinical use for the treatment of type 2 diabetes. To study metabolism and excretion of [(3)H]liraglutide, a single subcutaneous...
3.
Cooperative inhibitory effects of budesonide and formoterol on eosinophil superoxide production stimulated by bronchial epithelial cell conditioned medium
Persdotter S, Lindahl M, Malm-Erjefalt M, von Wachenfeldt K, Korn S, Stevens T, et al.
Int Arch Allergy Immunol . 2007 Feb; 143(3):201-10. PMID: 17290146
Background: Improved asthma control by combinations of inhaled glucocorticosteroids (GCs) and long-acting beta(2)-agonists (LABAs) includes a reduced frequency and severity of exacerbations. In view of the association of exacerbations with...
4.
Ketotifen induces primary necrosis of human eosinophils
Hasala H, Hasela H, Malm-Erjefalt M, Erjefalt J, Giembycz M, Zhang X, et al.
J Ocul Pharmacol Ther . 2005 Aug; 21(4):318-27. PMID: 16117696
Eosinophils are considered essential in the pathogenesis of allergy. Reduced eosinophil apoptosis is considered to be a key element in the formation of eosinophilia in allergic conditions. Antihistamines are widely...
5.
Interleukin-2-inducible T cell kinase regulates mast cell degranulation and acute allergic responses
Forssell J, Sideras P, Eriksson C, Malm-Erjefalt M, Rydell-Tormanen K, Ericsson P, et al.
Am J Respir Cell Mol Biol . 2005 Mar; 32(6):511-20. PMID: 15778496
Bruton's tyrosine kinase (Btk) is thought to positively regulate mast cell activation, implying a role in allergic responses. We have compared acute and late phase allergic airway reactions in mice...
6.
Discontinuous Percoll gradient centrifugation combined with immunomagnetic separation obviates the need for erythrocyte lysis and yields isolated eosinophils with minimal granule abnormalities
Malm-Erjefalt M, Stevens T, Persson C, Erjefalt J
J Immunol Methods . 2004 Jun; 288(1-2):99-109. PMID: 15183089
Isolated blood eosinophils are routinely used to study eosinophil activation mechanisms. However, as revealed by ultrastructural analysis, different isolation protocols may yield purified eosinophils with marked variability in granule electron...
7.
Acute allergic responses induce a prompt luminal entry of airway tissue eosinophils
Erjefalt J, Korsgren M, Malm-Erjefalt M, Conroy D, Williams T, Persson C
Am J Respir Cell Mol Biol . 2003 Mar; 29(4):439-48. PMID: 12663331
Traditionally, traffic and activation of eosinophils in asthmatic airways are thought to take place during the late-phase allergic reaction. The present study tests the hypothesis that when eosinophils are present...