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Monika Gullerova

Explore the profile of Monika Gullerova including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 782
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Recent Articles
1.
Long Q, Ajit K, Sedova K, Haluza V, Stefl R, Dokaneheifard S, et al.
Nucleic Acids Res . 2024 Oct; 52(21):13036-13056. PMID: 39445827
DNA double-strand breaks (DSBs) represent a lethal form of DNA damage that can trigger cell death or initiate oncogenesis. The activity of RNA polymerase II (RNAPII) at the break site...
2.
Ajit K, Gullerova M
Transcription . 2024 Oct; 15(3-5):161-175. PMID: 39353089
Genotoxic stress resulting from DNA damage is resolved through a signaling cascade known as the DNA Damage Response (DDR). The repair of damaged DNA is essential for cell survival, often...
3.
Glossop M, Chelysheva I, Ketley R, Alagia A, Gullerova M
Nucleic Acids Res . 2024 Aug; 52(20):12633-12649. PMID: 39119906
To ensure the integrity of our genetic code, a coordinated network of signalling and repair proteins, known as the DNA damage response (DDR), detects and repairs DNA insults, the most...
4.
Liu Z, Ajit K, Wu Y, Zhu W, Gullerova M
EMBO J . 2024 May; 43(12):2453-2485. PMID: 38719994
Double-strand breaks (DSBs) are the most lethal form of DNA damage. Transcriptional activity at DSBs, as well as transcriptional repression around DSBs, are both required for efficient DNA repair. The...
5.
Ajit K, Alagia A, Burger K, Gullerova M
Genome Res . 2024 Mar; 34(2):201-216. PMID: 38467418
DNA damage triggers a complex transcriptional response that involves both activation and repression of gene expression. In this study, we investigated global changes in transcription in response to ionizing irradiation...
6.
Zhang J, Chen F, Tang M, Xu W, Tian Y, Liu Z, et al.
Cell Rep . 2024 Feb; 43(2):113779. PMID: 38358891
R-loops are three-stranded structures that can pose threats to genome stability. RNase H1 precisely recognizes R-loops to drive their resolution within the genome, but the underlying mechanism is unclear. Here,...
7.
Long Q, Sebesta M, Sedova K, Haluza V, Alagia A, Liu Z, et al.
Cell Rep . 2023 Dec; 42(12):113489. PMID: 38039132
Double-strand breaks (DSBs) are the most severe type of DNA damage. Previously, we demonstrated that RNA polymerase II (RNAPII) phosphorylated at the tyrosine 1 (Y1P) residue of its C-terminal domain...
8.
Zhang X, Zhao Q, Wang T, Long Q, Sun Y, Jiao L, et al.
Ageing Res Rev . 2023 Nov; 92:102137. PMID: 38007046
Vascular aging is a major risk factor for age-related cardiovascular diseases, which have high rates of morbidity and mortality. It is characterized by changes in the blood vessels, such as...
9.
Alagia A, Terenova J, Ketley R, Di Fazio A, Chelysheva I, Gullerova M
Life Sci Alliance . 2023 Apr; 6(6). PMID: 37037596
Gene expression can be regulated by transcriptional or post-transcriptional gene silencing. Recently, we described nuclear nascent RNA silencing that is mediated by Dicer-dependent tRNA-derived small RNA molecules. In addition to...
10.
Alagia A, Ketley R, Gullerova M
STAR Protoc . 2023 Feb; 4(1):102096. PMID: 36825808
RNA transcribed at DNA double-strand breaks (DSBs) contributes to accurate DNA repair. Here, using the repair factors 53BP1 and TIRR as examples, we combine the fluorescence in situ hybridization (FISH)...