Monica Terrao
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Explore the profile of Monica Terrao including associated specialties, affiliations and a list of published articles.
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11
Citations
119
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Recent Articles
1.
Klimpel M, Terrao M, Brauer M, Dersch H, Biserni M, Melo Do Nascimento L, et al.
Biotechnol J
. 2024 May;
19(5):e2400090.
PMID: 38719592
The production of lentiviral vectors (LVs) pseudotyped with the vesicular stomatitis virus envelope glycoprotein (VSV-G) is limited by the associated cytotoxicity of the envelope and by the production methods used,...
2.
Vogel J, Terrao M, Schwingal S, Kapitza L, Brigulla D, Pirzas V, et al.
Biotechnol J
. 2024 Mar;
19(3):e2300348.
PMID: 38472091
The development and manufacture of biopharmaceuticals are subject to strict regulations that specify the required minimum quality of the products. A key measure to meet these quality requirements is the...
3.
Klimpel M, Terrao M, Ching N, Climenti V, Noll T, Pirzas V, et al.
Biotechnol Bioeng
. 2023 May;
120(9):2622-2638.
PMID: 37148430
The large-scale production of clinical-grade lentiviral vectors (LVs) for gene therapy applications is a remaining challenge. The use of adherent cell lines and methods like transient transfection are cost-intensive and...
4.
Melo Do Nascimento L, Terrao M, Kamanyi Marucha K, Liu B, Egler F, Clayton C
J Biol Chem
. 2020 Jun;
295(32):10940-10955.
PMID: 32532821
Control of gene expression in kinetoplastids such as trypanosomes depends heavily on RNA-binding proteins that influence mRNA decay and translation. We previously showed that the trypanosome protein MKT1 forms a...
5.
Montesinos-Rongen M, Terrao M, May C, Marcus K, Blumcke I, Hellmich M, et al.
Haematologica
. 2020 Mar;
106(3):708-717.
PMID: 32193251
The immunoglobulin (Ig) heavy and light chain variable gene mutational pattern of the B cell receptor (BCR) in primary central nervous system (CNS) lymphoma (PCNSL) cells suggests antigenic selection to...
6.
Terrao M, Marucha K, Mugo E, Droll D, Minia I, Egler F, et al.
Nucleic Acids Res
. 2018 Aug;
46(17):8993-9010.
PMID: 30124912
Trypanosoma brucei live in mammals as bloodstream forms and in the Tsetse midgut as procyclic forms. Differentiation from one form to the other proceeds via a growth-arrested stumpy form with...
7.
Klein C, Terrao M, Clayton C
PLoS One
. 2017 May;
12(5):e0177901.
PMID: 28545140
Kinetoplastids rely heavily on post-transcriptional mechanisms for control of gene expression, with regulation of mRNA processing, translation and degradation by RNA-binding proteins. ZC3H32 is a cytosolic mRNA-binding protein with three...
8.
Minia I, Merce C, Terrao M, Clayton C
PLoS Negl Trop Dis
. 2016 Sep;
10(9):e0004982.
PMID: 27606618
African trypanosome procyclic forms multiply in the midgut of tsetse flies, and are routinely cultured at 27°C. Heat shocks of 37°C and above result in general inhibition of translation, and...
9.
Antwi E, Haanstra J, Ramasamy G, Jensen B, Droll D, Rojas F, et al.
BMC Genomics
. 2016 Apr;
17:306.
PMID: 27118143
Background: Trypanosoma brucei is a unicellular parasite which multiplies in mammals (bloodstream form) and Tsetse flies (procyclic form). Trypanosome RNA polymerase II transcription is polycistronic, individual mRNAs being excised by...
10.
Klein C, Terrao M, Gil D, Clayton C
PLoS One
. 2015 Aug;
10(8):e0135973.
PMID: 26287607
We report here the results of experiments designed to identify RNA-binding proteins that might be associated with Trypanosoma brucei polysomes. After some preliminary mass spectrometry of polysomal fractions, we investigated...