Monica Hollstein
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Explore the profile of Monica Hollstein including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
3625
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Recent Articles
1.
Fearnley G, Latham A, Hollstein M, Odell A, Ponnambalam S
Cell Signal
. 2019 Nov;
66:109481.
PMID: 31760171
Cells respond to soluble and membrane-bound factors to activate signalling cascades that control cell proliferation and cell death. Vascular endothelial growth factor A (VEGF-A) is a soluble ligand that modulates...
2.
Zhivagui M, Ng A, Ardin M, Churchwell M, Pandey M, Renard C, et al.
Genome Res
. 2019 Mar;
29(4):521-531.
PMID: 30846532
Humans are frequently exposed to acrylamide, a probable human carcinogen found in commonplace sources such as most heated starchy foods or tobacco smoke. Prior evidence has shown that acrylamide causes...
3.
Huang M, Yu W, Teoh W, Ardin M, Jusakul A, Ng A, et al.
Genome Res
. 2017 Jul;
27(9):1475-1486.
PMID: 28739859
Aflatoxin B1 (AFB1) is a mutagen and IARC (International Agency for Research on Cancer) Group 1 carcinogen that causes hepatocellular carcinoma (HCC). Here, we present the first whole-genome data on...
4.
Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallee M, et al.
Sci Rep
. 2017 Jan;
7:40898.
PMID: 28091586
No abstract available.
5.
Kucab J, Hollstein M, Arlt V, Phillips D
Int J Cancer
. 2016 Nov;
140(4):877-887.
PMID: 27813088
TP53 mutations occur in half of all human tumours. Mutagen-induced or spontaneous TP53 mutagenesis can be studied in vitro using the human TP53 knock-in (Hupki) mouse embryo fibroblast (HUF) immortalisation...
6.
Bouaoun L, Sonkin D, Ardin M, Hollstein M, Byrnes G, Zavadil J, et al.
Hum Mutat
. 2016 Jun;
37(9):865-76.
PMID: 27328919
TP53 gene mutations are one of the most frequent somatic events in cancer. The IARC TP53 Database (http://p53.iarc.fr) is a popular resource that compiles occurrence and phenotype data on TP53...
7.
Jennis M, Kung C, Basu S, Budina-Kolomets A, Leu J, Khaku S, et al.
Genes Dev
. 2016 Apr;
30(8):918-30.
PMID: 27034505
A nonsynonymous single-nucleotide polymorphism at codon 47 in TP53 exists in African-descent populations (P47S, rs1800371; referred to here as S47). Here we report that, in human cell lines and a...
8.
Nik-Zainal S, Kucab J, Morganella S, Glodzik D, Alexandrov L, Arlt V, et al.
Mutagenesis
. 2015 Oct;
30(6):763-70.
PMID: 26443852
Whole genome sequencing of human tumours has revealed distinct patterns of mutation that hint at the causative origins of cancer. Experimental investigations of the mutations and mutation spectra induced by...
9.
Krais A, Muhlbauer K, Kucab J, Chinbuah H, Cornelius M, Wei Q, et al.
Toxicol In Vitro
. 2014 Sep;
29(1):34-43.
PMID: 25230394
We compared mouse embryonic stem (ES) cells and fibroblasts (MEFs) for their ability to metabolically activate the environmental carcinogens benzo[a]pyrene (BaP), 3-nitrobenzanthrone (3-NBA) and aristolochic acid I (AAI), measuring DNA...
10.
Olivier M, Weninger A, Ardin M, Huskova H, Castells X, Vallee M, et al.
Sci Rep
. 2014 Mar;
4:4482.
PMID: 24670820
Experimental models that recapitulate mutational landscapes of human cancers are needed to decipher the rapidly expanding data on human somatic mutations. We demonstrate that mutation patterns in immortalised cell lines...