Heinz H Schmeiser
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Explore the profile of Heinz H Schmeiser including associated specialties, affiliations and a list of published articles.
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123
Citations
1844
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Recent Articles
1.
Barta F, Dedikova A, Bebova M, Duskova S, Mraz J, Schmeiser H, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638820
The plant extract aristolochic acid (AA), containing aristolochic acids I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy (AAN) and Balkan endemic nephropathy (BEN), unique renal diseases...
2.
Schmeiser H, Muehlbauer K, Mier W, Baranski A, Neels O, Dimitrakopoulou-Strauss A, et al.
Mutagenesis
. 2019 May;
34(3):239-244.
PMID: 31107537
Radiopharmaceuticals used for diagnosis or therapy induce DNA strand breaks, which may be detectable by single-cell gel electrophoresis (called comet assay). Blood was taken from patients before and at different...
3.
Indra R, Cerna T, Heger Z, Hrabeta J, Wilhelm M, Dostalova S, et al.
Toxicology
. 2019 Mar;
419:40-54.
PMID: 30914192
Although ellipticine (Elli) is an efficient anticancer agent, it exerts several adverse effects. One approach to decrease the adverse effects of drugs is their encapsulation inside a suitable nanocarrier, allowing...
4.
Krais A, Kliem C, Arlt V, Schmeiser H
Electrophoresis
. 2019 Feb;
40(11):1535-1539.
PMID: 30767246
Methylating substances alter DNA by forming N3-methylthymidine (N3mT), a mutagenic base modification. To develop a sensitive analytical method for the detection of N3mT in DNA based on capillary electrophoresis with...
5.
Krais A, Park Y, Reifenberger G, Meister M, Plass C, Schmeiser H
Electrophoresis
. 2019 Feb;
40(9):1293-1297.
PMID: 30724377
A new sensitive analytical method using capillary electrophoresis with laser induced fluorescence (CE-LIF) was applied for the simultaneous detection of DNA methylation and hydroxymethylation levels in human cancers of different...
6.
Reed L, Indra R, Mrizova I, Moserova M, Schmeiser H, Wolf C, et al.
Toxicol Appl Pharmacol
. 2019 Jan;
366:64-74.
PMID: 30685480
The anticancer drug ellipticine exerts its genotoxic effects after metabolic activation by cytochrome P450 (CYP) enzymes. The present study has examined the role of cytochrome P450 oxidoreductase (POR) and cytochrome...
7.
Wohak L, Baranski A, Krais A, Schmeiser H, Phillips D, Arlt V
Mutagenesis
. 2018 Sep;
33(4):311-321.
PMID: 30215795
The tumour suppressor p53, encoded by TP53, is a key player in a wide network of signalling pathways. We investigated its role in the bioactivation of the environmental carcinogen 3-nitrobenzanthrone...
8.
Stiborova M, Dracinska H, Borek-Dohalska L, Klusonova Z, Holecova J, Martinkova M, et al.
Toxicology
. 2018 Apr;
400-401:48-56.
PMID: 29649501
Endocrine disruptors (EDs) are compounds that interfere with the balance of the endocrine system by mimicking or antagonising the effects of endogenous hormones, by altering the synthesis and metabolism of...
9.
Simoes M, Hockley S, Schwerdtle T, Gamboa da Costa G, Schmeiser H, Phillips D, et al.
Toxicol Appl Pharmacol
. 2018 Feb;
344:75.
PMID: 29471084
No abstract available.
10.
Reed L, Mrizova I, Barta F, Indra R, Moserova M, Kopka K, et al.
Arch Toxicol
. 2018 Jan;
92(4):1625-1638.
PMID: 29368147
Benzo[a]pyrene (BaP) is an environmental pollutant that, based on evidence largely from in vitro studies, exerts its genotoxic effects after metabolic activation by cytochrome P450s. In the present study, Hepatic...