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Mojca Frank-Bertoncelj

Explore the profile of Mojca Frank-Bertoncelj including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 526
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Recent Articles
1.
Burja B, Paul D, Tastanova A, Edalat S, Gerber R, Houtman M, et al.
Front Cell Dev Biol . 2022 May; 10:872688. PMID: 35573685
We present an optimized dissociation protocol for preparing high-quality skin cell suspensions for in-depth single-cell RNA-sequencing (scRNA-seq) analysis of fresh and cultured human skin. Our protocol enabled the isolation of...
2.
Kuret T, Frank-Bertoncelj M, Lakota K, Zigon P, Thallinger G, Kopitar A, et al.
Front Med (Lausanne) . 2022 Feb; 8:827095. PMID: 35127774
In the present study, we longitudinally monitored leukocyte subsets, expression of neutrophil surface adhesion molecules (CD62L and CD11b) and serum analytes in therapy-naïve patients with active giant cell arteritis (GCA)....
3.
Micheroli R, Elhai M, Edalat S, Frank-Bertoncelj M, Burki K, Ciurea A, et al.
RMD Open . 2022 Jan; 8(1). PMID: 34987094
Objectives: To integrate published single-cell RNA sequencing (scRNA-seq) data and assess the contribution of synovial fibroblast (SF) subsets to synovial pathotypes and respective clinical characteristics in treatment-naïve early arthritis. Methods:...
4.
Morante-Palacios O, Ciudad L, Micheroli R, de la Calle-Fabregat C, Li T, Barbisan G, et al.
Nucleic Acids Res . 2021 Dec; 50(1):108-126. PMID: 34893889
Glucocorticoids (GCs) exert potent anti-inflammatory effects in immune cells through the glucocorticoid receptor (GR). Dendritic cells (DCs), central actors for coordinating immune responses, acquire tolerogenic properties in response to GCs....
5.
Ge X, Frank-Bertoncelj M, Klein K, McGovern A, Kuret T, Houtman M, et al.
Genome Biol . 2021 Aug; 22(1):247. PMID: 34433485
Background: Genome-wide association studies have reported more than 100 risk loci for rheumatoid arthritis (RA). These loci are shown to be enriched in immune cell-specific enhancers, but the analysis so...
6.
Kuret T, Lakota K, cucnik S, Jurcic V, Distler O, Rotar Z, et al.
Int J Mol Sci . 2021 Jul; 22(12). PMID: 34204585
In this study, we explored expression of microRNA (miR), miR-target genes and matrix remodelling molecules in temporal artery biopsies (TABs) from treatment-naïve patients with giant cell arteritis (GCA, = 41)...
7.
Pachera E, Assassi S, Salazar G, Stellato M, Renoux F, Wunderlin A, et al.
J Clin Invest . 2020 Jul; 130(9):4888-4905. PMID: 32603313
TGF-β is a master regulator of fibrosis, driving the differentiation of fibroblasts into apoptosis-resistant myofibroblasts and sustaining the production of extracellular matrix (ECM) components. Here, we identified the nuclear long...
8.
Bolha L, Pizem J, Frank-Bertoncelj M, Hocevar A, Tomsic M, Jurcic V
Rheumatology (Oxford) . 2020 Jun; 59(11):3540-3552. PMID: 32594153
Objectives: To identify dysregulated microRNAs (miRNAs) and their gene targets in temporal arteries from GCA patients, and determine their association with GCA pathogenesis and related arterial wall remodelling. Methods: We...
9.
Burja B, Mertelj T, Frank-Bertoncelj M
Front Med (Lausanne) . 2020 May; 7:124. PMID: 32432116
The Janus kinase (JAK)-Signal transducer and activator of transcription (STAT) pathway is one of the central signaling hubs in inflammatory, immune and cancer cells. Inhibiting the JAK-STAT pathway with JAK...
10.
Stok U, Blokar E, Lenassi M, Holcar M, Frank-Bertoncelj M, Erman A, et al.
Cells . 2020 May; 9(5). PMID: 32414170
Antiphospholipid syndrome (APS) is a systemic autoimmune disease, characterized by thrombosis, obstetric complications and the presence of antiphospholipid antibodies (aPL), which drive endothelial injury and thrombophilia. Extracellular vesicles (EVs) have...