Mohammad Kohandel
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Explore the profile of Mohammad Kohandel including associated specialties, affiliations and a list of published articles.
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69
Citations
604
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Recent Articles
1.
Mao Y, Kim J, Podina L, Kohandel M
Sci Rep
. 2025 Jan;
15(1):3596.
PMID: 39875423
In the field of medical imaging, particularly MRI-based brain tumor classification, we propose an advanced convolutional neural network (CNN) leveraging the DenseNet-121 architecture, enhanced with dilated convolutional layers and Squeeze-and-Excitation...
2.
Sex-Related Differences in the Immune System Drive Differential Responses to Anti-PD-1 Immunotherapy
Cotra S, Kohandel M, Przedborski M
Biomolecules
. 2025 Jan;
14(12.
PMID: 39766221
Immune checkpoint inhibitors, such as anti-PD-1 antibodies, represent a significant advancement in cancer immunotherapy, but their efficacy varies notably between individuals, influenced by complex biological systems. Recent evidence suggests that...
3.
Lari S, Rajabzadeh H, Kohandel M, Kwon H
Math Biosci Eng
. 2024 Dec;
21(10):7337-7372.
PMID: 39696866
This study presented a novel approach for the precise ablation of breast tumors using focused ultrasound (FUS), leveraging a physics-informed neural network (PINN) integrated with a realistic breast model. FUS...
4.
Souri M, Elahi S, Moradi Kashkooli F, Kohandel M, Soltani M
NPJ Syst Biol Appl
. 2024 Nov;
10(1):136.
PMID: 39567549
Intratumoral delivery and localized chemotherapy have demonstrated promise in tumor treatment; however, the rapid drainage of therapeutic agents from well-vascularized tumors limits their ability to achieve maximum therapeutic efficacy. Therefore,...
5.
Abouali H, Przedborski M, Kohandel M, Poudineh M
Nanoscale
. 2024 Sep;
16(40):19062-19073.
PMID: 39319505
Anti-PD1 immune checkpoint blockade (ICB) has shown promising results for treating several aggressive cancers, enhancing patient survival rates. The variability in clinical response to anti-PD1 ICB is thought to be...
6.
Lari S, Kohandel M, Kwon H
Sci Rep
. 2024 Aug;
14(1):20042.
PMID: 39198623
The primary purpose of high-intensity focused ultrasound (HIFU), a non-invasive medical therapy, is to precisely target and ablate tumors by focusing high-frequency ultrasound from an external power source. A series...
7.
Moghimi N, Kamaraj M, Zehtabi F, Yavari S, Kohandel M, Khademhosseini A, et al.
J Mater Chem B
. 2024 Feb;
12(11):2818-2830.
PMID: 38411556
Personalized bone-regenerative materials have attracted substantial interest in recent years. Modern clinical settings demand the use of engineered materials incorporating patient-derived cells, cytokines, antibodies, and biomarkers to enhance the process...
8.
Mohammadrezaei D, Podina L, Silva J, Kohandel M
Biofabrication
. 2023 Dec;
16(2).
PMID: 38128119
The fields of regenerative medicine and cancer modeling have witnessed tremendous growth in the application of 3D bioprinting. Maintaining high cell viability throughout the bioprinting process is crucial for the...
9.
Mohammadi M, Sefidgar M, Aghanajafi C, Kohandel M, Soltani M
Cancers (Basel)
. 2023 Nov;
15(22).
PMID: 38001724
The present study develops a numerical model, which is the most complex one, in comparison to previous research to investigate drug delivery accompanied by the anti-angiogenesis effect. This paper simulates...
10.
Meaney C, Stapleton S, Kohandel M
Sci Rep
. 2023 Nov;
13(1):20548.
PMID: 37996509
Liposome-based anticancer agents take advantage of the increased vascular permeability and transvascular pressure gradients for selective accumulation in tumors, a phenomenon known as the enhanced permeability and retention(EPR) effect. The...