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Shiladitya Sengupta

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Articles 113
Citations 2504
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Recent Articles
1.
Brestoff J, Singh K, Aquilano K, Becker L, Berridge M, Boilard E, et al.
Nat Metab . 2025 Jan; 7(1):53-67. PMID: 39820558
Intercellular mitochondria transfer is an evolutionarily conserved process in which one cell delivers some of their mitochondria to another cell in the absence of cell division. This process has diverse...
2.
Baldwin J, Heuser-Loy C, Saha T, Schelker R, Slavkovic-Lukic D, Strieder N, et al.
Cell . 2024 Sep; 187(23):6614-6630.e21. PMID: 39276774
Mitochondrial loss and dysfunction drive T cell exhaustion, representing major barriers to successful T cell-based immunotherapies. Here, we describe an innovative platform to supply exogenous mitochondria to T cells, overcoming...
3.
Nath S, Sengupta S
J Chem Phys . 2024 Jul; 161(3). PMID: 39012814
It has been recognized of late that even amorphous, glass-forming materials in two dimensions (2D) are affected by Mermin-Wagner-type long wavelength thermal fluctuation, which is inconsequential in three dimensions (3D)....
4.
Saha T, Fojtu M, Nagar A, Thurakkal L, Srinivasan B, Mukherjee M, et al.
Sci Adv . 2024 Jun; 10(24):eadi2046. PMID: 38875335
The use of immune checkpoint inhibitors, which activate T cells, is a paradigm shift in the treatment of non-small cell lung cancer. However, the overall response remains low. To address...
5.
Namgung B, Dai H, Prathyushaa Vikraman P, Saha T, Sengupta S, Lin Jang H
Device . 2024 Apr; 2(3). PMID: 38617078
Three-dimensional (3D) cancer cell culture models such as tumor spheroids better recapitulate tumors than conventional two-dimensional (2D) models. However, two major challenges limit the routine use of 3D tumor spheroids....
6.
Lee V, Lee T, Ghosh A, Saha T, Bais M, Bharani K, et al.
Proc Natl Acad Sci U S A . 2024 Jan; 121(5):e2316170121. PMID: 38252814
Hemostatic devices are critical for managing emergent severe bleeding. With the increased use of anticoagulant therapy, there is a need for next-generation hemostats. We rationalized that a hemostat with an...
7.
Ghosh S, Sinha M, Samanta R, Sadhasivam S, Bhattacharyya A, Nandy A, et al.
Nat Biomed Eng . 2022 Oct; 6(10):1180-1195. PMID: 36229662
New antibiotics should ideally exhibit activity against drug-resistant bacteria, delay the development of bacterial resistance to them and be suitable for local delivery at desired sites of infection. Here, we...
8.
Nandi U, Patel P, Moid M, Nandi M, Sengupta S, Karmakar S, et al.
J Chem Phys . 2022 Jan; 156(1):014503. PMID: 34998317
A recent study introduced a novel mean-field model system where each particle over and above the interaction with its regular neighbors interacts with k extra pseudo-neighbors. Here, we present an...
9.
Saha T, Dash C, Jayabalan R, Khiste S, Kulkarni A, Kurmi K, et al.
Nat Nanotechnol . 2021 Nov; 17(1):98-106. PMID: 34795441
Cancer progresses by evading the immune system. Elucidating diverse immune evasion strategies is a critical step in the search for next-generation immunotherapies for cancer. Here we report that cancer cells...
10.
Saha T, Mondal J, Khiste S, Lusic H, Hu Z, Jayabalan R, et al.
Nanophotonics . 2021 Sep; 10(12):3063-3073. PMID: 34589378
Targeted delivery of drugs to tumor cells, which circumvent resistance mechanisms and induce cell killing, is a lingering challenge that requires innovative solutions. Here, we provide two bioengineered strategies in...