Mohammad Imran Siddiqi
Overview
Explore the profile of Mohammad Imran Siddiqi including associated specialties, affiliations and a list of published articles.
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Articles
136
Citations
741
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0
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Recent Articles
11.
Maurya P, Rawat R, Gupta S, Krishna S, Siddiqi M, Sashidhara K, et al.
J Biomol Struct Dyn
. 2024 Jan;
43(7):3390-3405.
PMID: 38179981
DNA topoisomerase 1 (Topo 1) is a pivotal player in various DNA processes, including replication, repair, and transcription. It serves as a target for anticancer drugs like camptothecin and its...
12.
Yadav K, Kuldeep J, Shabeer Ali H, Siddiqi M, Tripathi R
Life Sci
. 2023 Nov;
335:122271.
PMID: 37977356
Aims: Acquired drug resistance of Plasmodium is a global issue for the treatment of malaria. There are various proteases in the genome of Plasmodium falciparum (P. falciparum) including metacaspase-1 (PfMCA-1)...
13.
Soni M, Srivastava G, Ramalingam K, Shakya A, Siddiqi M, Pratap J
J Biomol Struct Dyn
. 2023 Nov;
42(24):13923-13938.
PMID: 37962849
Leishmaniasis is caused by ∼20 species of that affects millions in endemic areas. Available therapies are not sufficient to effectively control the disease, cause severe side effects and eventually lead...
14.
Kashyap K, Mahapatra P, Ahmed S, Buyukbingol E, Siddiqi M
J Chem Inf Model
. 2023 Oct;
63(20):6261-6282.
PMID: 37788831
Aldose reductase (ALR2) is a notable enzyme of the polyol pathway responsible for aggravating diabetic neuropathy complications. The first step begins when it catalyzes the reduction of glucose to sorbitol...
15.
Sinha K, Parwez S, Mv S, Yadav A, Siddiqi M, Banerjee D
J Biomol Struct Dyn
. 2023 Jul;
42(13):6823-6841.
PMID: 37504963
MMP-9, also known as gelatinase B, is a zinc-metalloproteinase family protein that plays a key role in the degradation of the extracellular matrix (ECM). The normal function of MMP-9 includes...
16.
Parwez S, Mahapatra P, Ahmed S, Siddiqi M
J Biomol Struct Dyn
. 2023 Jun;
42(11):5869-5880.
PMID: 37382224
Rheumatoid Arthritis (RA) is a well-known autoimmune inflammatory disease, distressing roughly 1% of the adult population throughout the globe. Many studies have suggested that overexpression of TNF-α, a pro-inflammatory cytokine,...
17.
Garg R, Katekar R, Parwez S, Agarwal A, Sahu S, Dadge S, et al.
Eur J Pharmacol
. 2023 Feb;
944:175559.
PMID: 36764353
Elevated plasma glucose concentration, as a consequence of excessive hepatic glucose production, plays a pivotal role in the development of diabetes. A chromogranin A-derived diabetogenic peptide Pancreastatin (PST) enhances hepatic...
18.
Singh J, Dubey S, Srivastava G, Siddiqi M, Srivastava S
Comput Biol Med
. 2022 Dec;
152:106392.
PMID: 36502697
COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged first around December 2019 in the city of Wuhan, China. Since then, several variants of the virus have emerged...
19.
Kashyap K, Panigrahi L, Ahmed S, Siddiqi M
Mol Inform
. 2022 Dec;
42(3):e2200113.
PMID: 36460626
Beta-site amyloid-β precursor protein-cleaving enzyme 1 (BACE1) is a transmembrane aspartic protease and has shown potential as a possible therapeutic target for Alzheimer's disease. This aggravating disease involves the aberrant...
20.
Kumari T, Verma D, Kuldeep J, Dhanabal V, Verma N, Sahai R, et al.
ACS Chem Biol
. 2022 Nov;
17(12):3420-3434.
PMID: 36367958
Naturally occurring cationic antimicrobial peptides (AMPs) mostly adopt α-helical structures in bacterial membrane mimetic environments. To explore the design of novel β-sheet AMPs, we identified two short cationic amphipathic β-strand...