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Mohammad Imran Siddiqi

Explore the profile of Mohammad Imran Siddiqi including associated specialties, affiliations and a list of published articles. Areas
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Articles 136
Citations 741
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Recent Articles
1.
Jaiswal A, Raj A, Kushawaha A, Maji B, Hemlata Bhatt , Verma S, et al.
Bioorg Chem . 2025 Feb; 157:108216. PMID: 39952063
This study explores a series of twenty-four newly synthesized pyrzole-dihydropyrimidinone hybrids as potential bone anabolic agents. Initially, an alkaline phosphatase assay, a common marker of bone formation, was used to...
2.
Khanka S, Rastogi S, Singh K, Sharma K, Parwez S, Siddiqi M, et al.
Biochem Pharmacol . 2025 Jan; 233:116751. PMID: 39800267
Glucocorticoid-induced osteoporosis (GIOP) is the most common type of secondary osteoporosis, marked by reduced bone density and impaired osteoblast function. Current treatments have serious side effects, highlighting the need for...
3.
Raj D, Nair A, Singh A, Basu S, Sarkar K, Sharma J, et al.
EMBO Rep . 2024 Dec; 26(3):656-689. PMID: 39695325
Salmonella enterica serotype Typhimurium (Salmonella) resides and multiplies intracellularly in cholesterol-rich compartments called Salmonella-containing vacuoles (SCVs) with actin-rich tubular extensions known as Salmonella-induced filaments (SIFs). SCV maturation depends on host-derived...
4.
Jaiswal R, Bhati G, Ahmed S, Siddiqi M
Mol Divers . 2024 Dec; PMID: 39648257
Triple-negative breast cancer (TNBC) lacks estrogen, progesterone, and HER2 expression, accounting for 15-20% of breast cancer cases. It is challenging due to low therapeutic response, heterogeneity, and aggressiveness. The PI3Ka...
5.
Kushavah U, Mahapatra P, Ahmed S, Siddiqi M
J Mol Model . 2024 Oct; 30(11):389. PMID: 39476191
Context: Alpha-glucosidase enzyme is considered an important therapeutic target for controlling hyperglycemia associated with type 2 diabetes. Novel scaffolds identified as potential alpha-glucosidase inhibitors from the Maybridge library utilizing pharmacophore...
6.
Kashyap K, Bhati G, Ahmed S, Siddiqi M
Int J Biol Macromol . 2024 Oct; 281(Pt 3):136438. PMID: 39389489
Parkinson's disease (PD) is one of the most prominent motor disorder of adult-onset dementia connected to memory and other cognitive abilities. Individuals with this vicious neurodegenerative condition tend to have...
7.
Shrivastava D, Abboud E, Ramchandra J, Jha A, Marq J, Chaurasia A, et al.
PLoS Pathog . 2024 Sep; 20(9):e1012593. PMID: 39348385
The Apicomplexa phylum encompasses numerous obligate intracellular parasites, some associated with severe implications for human health, including Plasmodium, Cryptosporidium, and Toxoplasma gondii. The iron-sulfur cluster [Fe-S] biogenesis ISC pathway, localized...
8.
Anand A, Gautam G, Srivastava G, Yadav S, Ramalingam K, Siddiqi M, et al.
Infect Immun . 2024 Sep; 92(10):e0023424. PMID: 39248465
Chaperonins/Heat shock protein 60 are ubiquitous multimeric protein complexes that assist in the folding of partially and/or misfolded proteins using metabolic energy into their native stage. The eukaryotic group II...
9.
Parwez S, Chaurasia A, Mahapatra P, Ahmed S, Siddiqi M
Mol Divers . 2024 Apr; PMID: 38662177
Cathepsin K is a type of cysteine proteinase that is primarily expressed in osteoclasts and has a key role in the breakdown of bone matrix protein during bone resorption. Many...
10.
Dutta M, Qamar T, Kushavah U, Siddiqi M, Kar S
Mol Divers . 2024 Mar; 28(6):4403-4424. PMID: 38522046
In order to combat various infectious diseases, the utilization of host-directed therapies as an alternative to chemotherapy has gained a lot of attention in the recent past, since it bypasses...