Mitchell E Menezes
Overview
Explore the profile of Mitchell E Menezes including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
654
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Recent Articles
11.
Emdad L, Janjic A, Alzubi M, Hu B, Santhekadur P, Menezes M, et al.
Neuro Oncol
. 2014 Sep;
17(3):419-29.
PMID: 25216670
Background: Malignant glioma is an aggressive cancer requiring new therapeutic targets. MicroRNAs (miRNAs) regulate gene expression post transcriptionally and are implicated in cancer development and progression. Deregulated expressions of several...
12.
Das S, Menezes M, Bhatia S, Wang X, Emdad L, Sarkar D, et al.
J Cell Physiol
. 2014 Sep;
230(2):259-71.
PMID: 25196387
Gene therapy, which involves replacement of a defective gene with a functional, healthy copy of that gene, is a potentially beneficial cancer treatment approach particularly over chemotherapy, which often lacks...
13.
Menezes M, Bhatia S, Bhoopathi P, Das S, Emdad L, Dasgupta S, et al.
Adv Exp Med Biol
. 2014 Jul;
818:127-53.
PMID: 25001534
First identified almost two decades ago as a novel gene differentially expressed in human melanoma cells induced to terminally differentiate, MDA-7/IL-24 has since shown great potential as an anti-cancer gene....
14.
Menezes M, Das S, Emdad L, Windle J, Wang X, Sarkar D, et al.
Adv Cancer Res
. 2014 Jun;
121:331-382.
PMID: 24889535
Elucidating the mechanism of pathogenesis of breast cancer has greatly benefited from breakthrough advances in both genetically engineered mouse (GEM) models and xenograft transplantation technologies. The vast array of breast...
15.
Kegelman T, Das S, Hu B, Bacolod M, Fuller C, Menezes M, et al.
Neuro Oncol
. 2013 Dec;
16(1):50-61.
PMID: 24305713
Background: The extraordinary invasiveness of human glioblastoma multiforme (GBM) contributes to treatment failure and the grim prognosis of patients diagnosed with this tumor. Consequently, it is imperative to define further...
16.
Dasgupta S, Menezes M, Das S, Emdad L, Janjic A, Bhatia S, et al.
Clin Cancer Res
. 2013 Jul;
19(17):4621-33.
PMID: 23873690
Purpose: Urothelial cell carcinoma (UCC) rapidly progresses from superficial to muscle-invasive tumors. The key molecules involved in metastatic progression and its early detection require clarification. The present study defines a...
17.
Bhatia S, Menezes M, Das S, Emdad L, Dasgupta S, Wang X, et al.
Discov Med
. 2013 Jun;
15(84):309-17.
PMID: 23725604
Gene therapy provides a novel platform for therapeutic intervention of several genetic and non-genetic disorders. With the recent developments in the field, a wide variety of viral and non-viral vectors...
18.
Bhutia S, Das S, Azab B, Menezes M, Dent P, Wang X, et al.
Int J Cancer
. 2013 May;
133(11):2726-36.
PMID: 23720015
Melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) displays a broad range of antitumor properties including cancer-specific induction of apoptosis, inhibition of tumor angiogenesis and modulation of antitumor immune responses. In our study, we...
19.
Hedvat M, Emdad L, Das S, Kim K, Dasgupta S, Thomas S, et al.
Anticancer Agents Med Chem
. 2012 Aug;
12(9):1143-55.
PMID: 22931411
Structure-based modeling combined with rational drug design, and high throughput screening approaches offer significant potential for identifying and developing lead compounds with therapeutic potential. The present review focuses on these...
20.
Andrews J, Sykora L, Letostak T, Menezes M, Mitra A, Barik S, et al.
Exp Cell Res
. 2012 Apr;
318(10):1086-93.
PMID: 22504047
HSP40 family member MRJ (DNAJB6) has been in the spot light for its relevance to Huntington's, Parkinson's diseases, limb-girdle muscular dystrophy, placental development, neural stem cells, cell cycle and malignancies...