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» Authors » Miriam Verhoef-Post

Miriam Verhoef-Post

Explore the profile of Miriam Verhoef-Post including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 186
Followers 0
Related Specialties
Endocrinology
Molecular Biology
Cell Biology
Top 10 Co-Authors
Axel P N Themmen
Djura Piersma
Els M J J Berns
Huibert A P Pols
Frank H de Jong
Stenvert L S Drop
Andre G Uitterlinden
Leo Hofland
T Martijn Kuijper
Martijn Bruysters
Published In
J Clin Endocrinol Metab
Mol Cell Endocrinol
Semin Reprod Med
Plant J
J Biol Chem
Affiliations
Soon will be listed here.
Recent Articles
1.
Rapid identification of lettuce seed germination mutants by bulked segregant analysis and whole genome sequencing
Huo H, Henry I, Coppoolse E, Verhoef-Post M, Schut J, de Rooij H, et al.
Plant J . 2016 Jul; 88(3):345-360. PMID: 27406937
Lettuce (Lactuca sativa) seeds exhibit thermoinhibition, or failure to complete germination when imbibed at warm temperatures. Chemical mutagenesis was employed to develop lettuce lines that exhibit germination thermotolerance. Two independent...
2.
Mutation analysis of the LH receptor gene in Leydig cell adenoma and hyperplasia and functional and biochemical studies of activating mutations of the LH receptor gene
Boot A, Lumbroso S, Verhoef-Post M, Richter-Unruh A, Looijenga L, Funaro A, et al.
J Clin Endocrinol Metab . 2011 Apr; 96(7):E1197-205. PMID: 21490077
Context: Germline and somatic activating mutations in the LH receptor (LHR) gene have been reported. Objective: Our objective was to perform mutation analysis of the LHR gene of patients with...
3.
Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization
Delhanty P, van Kerkwijk A, Huisman M, van de Zande B, Verhoef-Post M, Gauna C, et al.
Am J Physiol Endocrinol Metab . 2010 Jul; 299(3):E497-505. PMID: 20587751
The composition of the plasma membrane affects the responsiveness of cells to metabolically important hormones such as insulin and vasoactive intestinal peptide. Ghrelin is a metabolically regulated hormone that activates...
4.
LH receptor gene expression is essentially absent in breast tumor tissue: implications for treatment
Kuijper T, Ruigrok-Ritstier K, Verhoef-Post M, Piersma D, Bruysters M, Berns E, et al.
Mol Cell Endocrinol . 2009 Apr; 302(1):58-64. PMID: 19356624
Worldwide, breast cancer is the most frequently occurring malignancy in women. Early age at full term pregnancy has a protective effect against breast cancer. Evidence coming from a rat breast...
5.
Asp330 and Tyr331 in the C-terminal cysteine-rich region of the luteinizing hormone receptor are key residues in hormone-induced receptor activation
Bruysters M, Verhoef-Post M, Themmen A
J Biol Chem . 2008 Jul; 283(38):25821-8. PMID: 18641392
The luteinizing hormone (LH) receptor plays an essential role in male and female gonadal function. Together with the follicle-stimulating hormone (FSH) and thyroid stimulating hormone (TSH) receptors, the LH receptor...
6.
Polymorphic variations in exon 10 of the luteinizing hormone receptor: functional consequences and associations with breast cancer
Piersma D, Verhoef-Post M, Look M, Uitterlinden A, Pols H, Berns E, et al.
Mol Cell Endocrinol . 2007 Aug; 276(1-2):63-70. PMID: 17709176
Polymorphic variation of the LHR gene may affect receptor function and accordingly may influence ovarian steroid hormone action, including steroid hormone-dependent clinical outcome. The functional effects of two single nucleotide...
7.
LH receptor gene mutations and polymorphisms: an overview
Piersma D, Verhoef-Post M, Berns E, Themmen A
Mol Cell Endocrinol . 2006 Oct; 260-262:282-6. PMID: 17030087
No abstract available.
8.
A common polymorphism renders the luteinizing hormone receptor protein more active by improving signal peptide function and predicts adverse outcome in breast cancer patients
Piersma D, Berns E, Verhoef-Post M, Uitterlinden A, Braakman I, Pols H, et al.
J Clin Endocrinol Metab . 2006 Feb; 91(4):1470-6. PMID: 16464948
Context: Epidemiological and animal studies indicate a carcinogenic role of estrogens in breast tissue. The pituitary gonadotropin LH is an important regulator of estrogen production in premenopausal women, whereas even...
9.
Insight into mutation-induced activation of the luteinizing hormone receptor: molecular simulations predict the functional behavior of engineered mutants at M398
Fanelli F, Verhoef-Post M, Timmerman M, Zeilemaker A, Martens J, Themmen A
Mol Endocrinol . 2004 Mar; 18(6):1499-508. PMID: 15016840
In this study, molecular simulations have been combined with site-directed mutagenesis experiments to explore M398(2.43), a LH (lutropin) receptor (LHR) site in helix 2 susceptible to spontaneous activating mutations, and...
10.
Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro
Feelders R, Lamberts S, Hofland L, Van Koetsveld P, Verhoef-Post M, Themmen A, et al.
J Clin Endocrinol Metab . 2003 Jan; 88(1):230-7. PMID: 12519858
In a substantial part of adrenal adenomas and hyperplasias from patients with Cushing's syndrome, cortisol production is controlled by the expression of aberrant hormone receptors on adrenocortical cells. We present...