Mikyoung You
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Explore the profile of Mikyoung You including associated specialties, affiliations and a list of published articles.
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13
Citations
113
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Recent Articles
1.
You M, Shamseldin H, Fogle H, Rushing B, AlMalki R, Jaafar A, et al.
Clin Genet
. 2024 Jan;
105(5):488-498.
PMID: 38193334
ALDH1L2, a mitochondrial enzyme in folate metabolism, converts 10-formyl-THF (10-formyltetrahydrofolate) to THF (tetrahydrofolate) and CO. At the cellular level, deficiency of this NADP-dependent reaction results in marked reduction in NADPH/NADP...
2.
Rushing B, Fogle H, Sharma J, You M, McCormac J, Molina S, et al.
Molecules
. 2022 Dec;
27(23).
PMID: 36500483
Folate (vitamin B9) is involved in one-carbon transfer reactions and plays a significant role in nucleic acid synthesis and control of cellular proliferation, among other key cellular processes. It is...
3.
Lee Y, Kim H, You M, Kim H
Nutrients
. 2022 Oct;
14(20).
PMID: 36296933
Although the red pepper and its seeds have been studied for metabolic diseases, the effects and potential mechanisms of red pepper seed extract (RPS) on hepatic lipid accumulation are not...
4.
You M, Wang Z, Kim H, Lee Y, Kim H
Nutr Res Pract
. 2022 Oct;
16(5):577-588.
PMID: 36238377
Background/objectives: Poorly regulated inflammation is believed to be the most predominant factor that can result in a wide scope of diseases including atopic dermatitis (AD). Despite many studies on the...
5.
Xu P, You M, Yu S, Luan Y, Eldani M, Caffrey T, et al.
Sci Rep
. 2022 Feb;
12(1):1659.
PMID: 35102236
Pancreatic ductal adenocarcinoma (PDAC) patients display distinct phenotypes of cachexia development, with either adipose tissue loss preceding skeletal muscle wasting or loss of only adipose tissue. Activin A levels were...
6.
Luan Y, Zhang Y, Yu S, You M, Xu P, Chung S, et al.
J Cachexia Sarcopenia Muscle
. 2022 Jan;
13(2):1289-1301.
PMID: 35044098
Background: Cancer-associated cachexia (CAC) is a complex syndrome of progressive muscle wasting and adipose loss with metabolic dysfunction, severely increasing the morbidity and mortality risk in cancer patients. However, there...
7.
Yook J, You M, Kim J, Toney A, Fan R, Puniya B, et al.
Proc Natl Acad Sci U S A
. 2021 Oct;
118(40).
PMID: 34593646
Iron is an essential biometal, but is toxic if it exists in excess. Therefore, iron content is tightly regulated at cellular and systemic levels to meet metabolic demands but to...
8.
Yook J, Thomas S, Toney A, You M, Kim Y, Liu Z, et al.
J Nutr
. 2021 Aug;
151(10):2967-2975.
PMID: 34383942
Background: Adaptive thermogenesis is an iron-demanding pathway, significantly contributing to whole-body energy expenditure. However, the effects of iron-deficient diets on adaptive thermogenesis and obesity remain unknown. Objectives: We aimed to...
9.
Yook J, You M, Kim Y, Zhou M, Liu Z, Kim Y, et al.
J Biol Chem
. 2021 Feb;
296:100452.
PMID: 33631196
The development of thermogenic adipocytes concurs with mitochondrial biogenesis, an iron-dependent pathway. Iron regulatory proteins (IRP) 1 and 2 are RNA-binding proteins that regulate intracellular iron homeostasis. IRPs bind to...
10.
You M, Lee Y, Kim H, Kook J, Kim H
Nutrients
. 2020 Oct;
12(10).
PMID: 33080824
The rational regulation of programmed cell death by means of autophagy and apoptosis has been considered a potential treatment strategy for cancer. We demonstrated the inhibitory effect of St. John's...