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Miguel Fidalgo

Explore the profile of Miguel Fidalgo including associated specialties, affiliations and a list of published articles. Areas
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Articles 48
Citations 1703
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Recent Articles
1.
Heraud-Farlow J, Taylor S, Chalk A, Escudero A, Hu S, Goradia A, et al.
Sci Immunol . 2024 Nov; 9(101):eadk0412. PMID: 39576872
Adenosine-to-inosine (A-to-I) editing of double-stranded RNA (dsRNA) by ADAR1 is an essential modifier of the immunogenicity of cellular dsRNA. The role of MDA5 in sensing unedited cellular dsRNA and the...
2.
Fondevila M, Novoa E, Fernandez U, Dorta V, Parracho T, Kreimeyer H, et al.
Mol Metab . 2024 May; 85:101962. PMID: 38815625
Objective: p63 is a transcription factor involved in multiple biological functions. In the liver, the TAp63 isoform induces lipid accumulation in hepatocytes. However, the role of liver TAp63 in the...
3.
Novoa E, da Silva Lima N, Gonzalez-Rellan M, Chantada-Vazquez M, Verheij J, Rodriguez A, et al.
Hepatology . 2024 May; PMID: 38761407
Background And Aims: Mitochondrial antiviral signaling protein (MAVS) is a critical regulator that activates the host's innate immunity against RNA viruses, and its signaling pathway has been linked to the...
4.
Wu Q, Carlos A, Braza F, Bergman M, Kitoko J, Bastos-Amador P, et al.
EMBO J . 2024 Mar; 43(8):1445-1483. PMID: 38499786
Regulatory T (TREG) cells develop via a program orchestrated by the transcription factor forkhead box protein P3 (FOXP3). Maintenance of the TREG cell lineage relies on sustained FOXP3 transcription via...
5.
Fernandez-Rial C, Fidalgo M
Cell Reprogram . 2024 Feb; 26(1):8-9. PMID: 38300527
Developing cell models that faithfully replicate the molecular and functional traits of cells from the earliest stages of mammalian development presents a significant challenge. The strategic induction of signal transducer...
6.
Capelo-Diz A, Lachiondo-Ortega S, Fernandez-Ramos D, Canas-Martin J, Goikoetxea-Usandizaga N, Serrano-Macia M, et al.
Cell Metab . 2023 Aug; 35(8):1373-1389.e8. PMID: 37527658
There has been an intense focus to uncover the molecular mechanisms by which fasting triggers the adaptive cellular responses in the major organs of the body. Here, we show that...
7.
Gonzalez-Rellan M, Parracho T, Heras V, Rodriguez A, Fondevila M, Novoa E, et al.
Mol Metab . 2023 Jul; 75:101776. PMID: 37453647
Objective: O-GlcNAcylation is a post-translational modification that directly couples the processes of nutrient sensing, metabolism, and signal transduction, affecting protein function and localization, since the O-linked N-acetylglucosamine moiety comes directly...
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Malik V, Zang R, Fuentes-Iglesias A, Huang X, Li D, Fidalgo M, et al.
Life Sci Alliance . 2022 Aug; 5(11). PMID: 35961778
Extended pluripotent or expanded potential stem cells (EPSCs) possess superior developmental potential to embryonic stem cells (ESCs). However, the molecular underpinning of EPSC maintenance in vitro is not well defined....
10.
Pena-Leon V, Folgueira C, Barja-Fernandez S, Perez-Lois R, da Silva Lima N, Martin M, et al.
Nat Metab . 2022 Jul; 4(7):901-917. PMID: 35879461
Early-life determinants are thought to be a major factor in the rapid increase of obesity. However, while maternal nutrition has been extensively studied, the effects of breastfeeding by the infant...