Miguel Fidalgo
Overview
Explore the profile of Miguel Fidalgo including associated specialties, affiliations and a list of published articles.
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48
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1703
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Recent Articles
11.
Gonzalez-Rellan M, Novoa E, da Silva Lima N, Rodriguez A, Veyrat-Durebex C, Seoane S, et al.
Gut
. 2022 May;
72(3):472-483.
PMID: 35580962
Objective: p63 is a transcription factor within the p53 protein family that has key roles in development, differentiation and prevention of senescence, but its metabolic actions remain largely unknown. Herein,...
12.
Covelo-Molares H, Souto Y, Fidalgo M, Guallar D
Methods Mol Biol
. 2021 Oct;
2520:199-213.
PMID: 34611821
Embryonic stem cells (ESCs) are derived from the inner cell mass of the preimplantation blastocyst and can be maintained indefinitely in vitro without losing their properties. Given their self-renewal and...
13.
da Silva Lima N, Fondevila M, Novoa E, Buque X, Mercado-Gomez M, Gallet S, et al.
J Hepatol
. 2021 Sep;
76(1):11-24.
PMID: 34555423
Background & Aims: Autophagy-related gene 3 (ATG3) is an enzyme mainly known for its actions in the LC3 lipidation process, which is essential for autophagy. Whether ATG3 plays a role...
14.
Gonzalez-Rellan M, Fondevila M, Fernandez U, Rodriguez A, Varela-Rey M, Veyrat-Durebex C, et al.
Nat Commun
. 2021 Aug;
12(1):5068.
PMID: 34417460
p53 regulates several signaling pathways to maintain the metabolic homeostasis of cells and modulates the cellular response to stress. Deficiency or excess of nutrients causes cellular metabolic stress, and we...
15.
Wang J, Yu H, Ma Q, Zeng P, Wu D, Hou Y, et al.
Cell Stem Cell
. 2021 May;
28(10):1868-1883.e11.
PMID: 34038708
Topological-associated domains (TADs) are thought to be relatively stable across cell types, although some TAD reorganization has been observed during cellular differentiation. However, little is known about the mechanisms through...
16.
Fuentes-Iglesias A, Ameneiro C, Guallar D, Fidalgo M
Methods Mol Biol
. 2021 Mar;
2454:743-754.
PMID: 33689163
The reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has proven to be a powerful system creating new opportunities to interrogate molecular mechanisms controlling cell fate determination. Under...
17.
Garcia-Outeiral V, de la Parte C, Fidalgo M, Guallar D
Front Cell Dev Biol
. 2021 Feb;
8:630754.
PMID: 33537318
Ten-eleven translocation-2 (TET2) is a crucial driver of cell fate outcomes in a myriad of biological processes, including embryonic development and tissue homeostasis. TET2 catalyzes the demethylation of 5-methylcytosine on...
18.
Lan J, Rajan N, Bizet M, Penning A, Singh N, Guallar D, et al.
Nat Commun
. 2020 Oct;
11(1):4956.
PMID: 33009383
Tet-enzyme-mediated 5-hydroxymethylation of cytosines in DNA plays a crucial role in mouse embryonic stem cells (ESCs). In RNA also, 5-hydroxymethylcytosine (5hmC) has recently been evidenced, but its physiological roles are...
19.
Fuentes-Iglesias A, Garcia-Outeiral V, Pardavila J, Wang J, Fidalgo M, Guallar D
STAR Protoc
. 2020 Sep;
1(2).
PMID: 32995755
RNA-binding proteins are key regulators of cell identity and function, which underscores the need for unbiased and versatile protocols to identify and characterize novel protein-RNA interactions. Here, we describe a...
20.
Guallar D, Fuentes-Iglesias A, Souto Y, Ameneiro C, Freire-Agulleiro O, Pardavila J, et al.
Cell Stem Cell
. 2020 May;
27(2):300-314.e11.
PMID: 32396862
RNA editing of adenosine to inosine (A to I) is catalyzed by ADAR1 and dramatically alters the cellular transcriptome, although its functional roles in somatic cell reprogramming are largely unexplored....