Michelle M Nicolle
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Explore the profile of Michelle M Nicolle including associated specialties, affiliations and a list of published articles.
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18
Citations
500
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Recent Articles
1.
McQuail J, Nicolle M
Neurobiol Aging
. 2014 Aug;
36(1):323-33.
PMID: 25086838
Fischer 344 × Brown Norway F1 (F344 × BN-F1) hybrid rats express greater longevity with improved health relative to aging rodents of other strains; however, few behavioral reports have thoroughly...
2.
McQuail J, Davis K, Miller F, Hampson R, Deadwyler S, Howlett A, et al.
Neuropharmacology
. 2013 Jan;
70:63-73.
PMID: 23347951
Normal aging may limit the signaling efficacy of certain GPCRs by disturbing the function of specific Gα-subunits and leading to deficient modulation of intracellular functions that subserve synaptic plasticity, learning...
3.
McQuail J, Banuelos C, LaSarge C, Nicolle M, Bizon J
Neurobiol Aging
. 2011 Dec;
33(6):1124.e1-12.
PMID: 22169202
Gamma aminobutyric acid (GABA)(B) receptors (GABA(B)Rs) have been linked to a wide range of physiological and cognitive processes and are of interest for treating a number of neurodegenerative and psychiatric...
4.
Nieves-Martinez E, Haynes K, Childers S, Sonntag W, Nicolle M
Behav Brain Res
. 2011 Nov;
227(1):258-64.
PMID: 22085876
Behavioral flexibility, the ability to modify responses due to changing task demands, is detrimentally affected by aging with a shift towards increased cognitive rigidity. The neurobiological basis of this cognitive...
5.
Sergeant S, McQuail J, Riddle D, Chilton F, Ortmeier S, Jessup J, et al.
J Gerontol A Biol Sci Med Sci
. 2011 Mar;
66(5):521-33.
PMID: 21393424
Fish oil (FO) mediates a number of cardioprotective benefits in patients with cardiovascular disease. In the absence of cardiovascular disease, however, the effects of FO on cardiac structure and function...
6.
Shi L, Olson J, DAgostino Jr R, Linville C, Nicolle M, Robbins M, et al.
Brain Res
. 2011 Feb;
1385:307-16.
PMID: 21338580
Fractionated partial or whole-brain irradiation (fWBI) is a widely used, effective treatment for primary and metastatic brain tumors, but it also produces radiation-induced brain injury, including cognitive impairment. Radiation-induced neural...
7.
McQuail J, Riddle D, Nicolle M
Neurobiol Aging
. 2010 Jun;
32(12):2322.e1-4.
PMID: 20561717
Degeneration of the cholinergic neurons in the basal forebrain and elevation of inflammatory markers are well-established hallmarks of Alzheimer's disease; however, the interplay of these processes in normal aging is...
8.
Shirey J, Brady A, Jones P, Davis A, Bridges T, Kennedy J, et al.
J Neurosci
. 2009 Nov;
29(45):14271-86.
PMID: 19906975
M(1) muscarinic acetylcholine receptors (mAChRs) may represent a viable target for treatment of disorders involving impaired cognitive function. However, a major limitation to testing this hypothesis has been a lack...
9.
Zhuo J, Prakasam A, Murray M, Zhang H, Baxter M, Sambamurti K, et al.
Curr Alzheimer Res
. 2008 Aug;
5(4):385-91.
PMID: 18690835
The medial temporal lobe-dependent memory loss associated with Alzheimer's disease (AD) is often accompanied by a loss of prefrontal cortex-dependent cognitive domains that fall under the broad category of executive...
10.
Kukar T, Prescott S, Eriksen J, Holloway V, Murphy M, Koo E, et al.
BMC Neurosci
. 2007 Jul;
8:54.
PMID: 17650315
Background: Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a reduced incidence of Alzheimer's disease (AD). We and others have shown that certain NSAIDs reduce secretion of Abeta42...