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Melissa E Murray

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Articles 246
Citations 12662
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Recent Articles
1.
Ghatamaneni S, Hruska C, Shin I, Bruinsma T, Scott N, Lee J, et al.
Acta Neuropathol . 2025 Mar; 149(1):26. PMID: 40085238
Recent developments in tau positron emission tomography (PET) radiotracers have enhanced the visualization of tau aggregates in Alzheimer's disease (AD). The maturity level of neurofibrillary tangles can affect its recognition...
2.
Morderer D, Wren M, Liu F, Kouri N, Maistrenko A, Khalil B, et al.
Mol Neurodegener . 2025 Mar; 20(1):32. PMID: 40082954
Background: Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mechanisms underlying the diversity of neuronal and...
3.
Ono D, Sekiya H, Maier A, Murray M, Koga S, Dickson D
Alzheimers Dement . 2025 Mar; 21(3):e14628. PMID: 40042515
Introduction: Parkinsonism in patients with Alzheimer's disease (AD) is often attributed to Lewy-related pathology, given its high comorbidity. In the era of anti-amyloid therapy, recognizing parkinsonism caused by AD pathology...
4.
Oatman S, Reddy J, Atashgaran A, Wang X, Min Y, Quicksall Z, et al.
bioRxiv . 2025 Mar; PMID: 40027794
Alzheimer's disease (AD) brains are characterized by neuropathologic and biochemical changes that are highly variable across individuals. Capturing epigenetic factors that associate with this variability can reveal novel biological insights...
5.
Wang H, Xiang J, Yuan C, Veire A, Gendron T, Murray M, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(9):e2419818122. PMID: 39999167
Repeat expansions in the gene are the most common genetic cause of amyotrophic lateral sclerosis and familial frontotemporal dementia (ALS/FTD). To identify molecular defects that take place in the dorsolateral...
6.
Wisse L, Wuestefeld A, Murray M, Jagust W, La Joie R
Alzheimers Dement . 2025 Feb; 21(2):e14582. PMID: 39985478
Hippocampal atrophy on magnetic resonance imaging is an important biomarker in Alzheimer's disease (AD). While hippocampal atrophy was thought to result from tau tangles in AD, different neuropathologies can lead...
7.
Katsumi Y, Touroutoglou A, Brickhouse M, Eloyan A, Eckbo R, Zaitsev A, et al.
Alzheimers Dement . 2025 Feb; 21(2):e14489. PMID: 39968692
Introduction: Early-onset and late-onset Alzheimer's disease (EOAD and LOAD, respectively) have distinct clinical manifestations, with prior work based on small samples suggesting unique patterns of neurodegeneration. The current study performed...
8.
Ebner B, Erdahl S, Lundgreen C, Vassilaki M, Kremers W, Knopman D, et al.
Acta Neuropathol . 2025 Feb; 149(1):18. PMID: 39954128
We examined whether total joint arthroplasty (TJA) is associated with increased metal accumulation in the brain and histopathologic changes of Alzheimer's disease. We measured ultra-trace metal concentrations (aluminum, chromium, cobalt,...
9.
Rabinovici G, Knopman D, Arbizu J, Benzinger T, Donohoe K, Hansson O, et al.
J Nucl Med . 2025 Jan; PMID: 39778970
The Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) and to...
10.
Rabinovici G, Knopman D, Arbizu J, Benzinger T, Donohoe K, Hansson O, et al.
Alzheimers Dement . 2025 Jan; 21(1):e14338. PMID: 39776249
Introduction: The Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) and...