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Michele Egger

Explore the profile of Michele Egger including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 937
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Recent Articles
1.
Muller K, Honcharova-Biletska H, Koppe C, Egger M, Chan L, Schneider A, et al.
Proc Natl Acad Sci U S A . 2021 Apr; 118(12). PMID: 33798093
The c-Jun N-terminal kinase (JNK) signaling pathway mediates adaptation to stress signals and has been associated with cell death, cell proliferation, and malignant transformation in the liver. However, up to...
2.
Friemel J, Frick L, Unger K, Egger M, Parrotta R, Boge Y, et al.
Mol Cancer Res . 2019 Apr; 17(7):1493-1502. PMID: 30967480
Murine liver tumors often fail to recapitulate the complexity of human hepatocellular carcinoma (HCC), which might explain the difficulty to translate preclinical mouse studies into clinical science. The aim of...
3.
Ma C, Kesarwala A, Eggert T, Medina-Echeverz J, Kleiner D, Jin P, et al.
Nature . 2016 Mar; 531(7593):253-7. PMID: 26934227
Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death. Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the US population and is considered to be...
4.
Kohler U, Bohm F, Rolfs F, Egger M, Hornemann T, Pasparakis M, et al.
J Hepatol . 2015 Sep; 64(1):94-102. PMID: 26348541
Background & Aims: The liver is frequently challenged by toxins and reactive oxygen species. Therefore, hepatocytes require cytoprotective strategies to cope with these insults. Since the transcription factors Nrf2 and...
5.
Wolf M, Adili A, Piotrowitz K, Abdullah Z, Boege Y, Stemmer K, et al.
Cancer Cell . 2014 Oct; 26(4):549-64. PMID: 25314080
Hepatocellular carcinoma (HCC), the fastest rising cancer in the United States and increasing in Europe, often occurs with nonalcoholic steatohepatitis (NASH). Mechanisms underlying NASH and NASH-induced HCC are largely unknown....
6.
Friemel J, Rechsteiner M, Frick L, Bohm F, Struckmann K, Egger M, et al.
Clin Cancer Res . 2014 Sep; 21(8):1951-61. PMID: 25248380
Purpose: Morphologic intratumor heterogeneity is well known to exist in hepatocellular carcinoma (HCC), but very few systematic analyses of this phenomenon have been performed. The aim of this study was...