Michela Di Virgilio
Overview
Explore the profile of Michela Di Virgilio including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1950
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0
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Recent Articles
1.
Kabrani E, Rahjouei A, Berruezo-Llacuna M, Ebeling S, Saha T, Altwasser R, et al.
Nat Commun
. 2025 Jan;
16(1):777.
PMID: 39824820
The establishment of protective immune responses relies on the ability of terminally differentiated B cells to secrete a broad variety of antigen-specific antibodies with different effector functions. RIF1 is a...
2.
Malzl D, Peycheva M, Rahjouei A, Gnan S, Klein K, Nazarova M, et al.
Nat Commun
. 2023 Dec;
14(1):8049.
PMID: 38081811
The mammalian DNA replication timing (RT) program is crucial for the proper functioning and integrity of the genome. The best-known mechanism for controlling RT is the suppression of late origins...
3.
Dauben H, Matic I, Kidmose R, Pedersen B, Saha T, Di Virgilio M, et al.
Trends Biochem Sci
. 2023 Nov;
48(12):1009-1011.
PMID: 37949052
No abstract available.
4.
Kabrani E, Saha T, Di Virgilio M
Trends Immunol
. 2023 Aug;
44(10):782-791.
PMID: 37640588
The DNA double-strand break (DSB) repair factor 53BP1 has long been implicated in V(D)J and class switch recombination (CSR) of mammalian lymphocyte receptors. However, the dissection of the underlying molecular...
5.
Schneider J, Sundaravinayagam D, Blume A, Marg A, Grunwald S, Metzler E, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769095
Critical illness myopathy (CIM) is an acquired, devastating, multifactorial muscle-wasting disease with incomplete recovery. The impact on hospital costs and permanent loss of quality of life is enormous. Incomplete recovery...
6.
Balasubramanian S, Andreani M, Andrade J, Saha T, Sundaravinayagam D, Garzon J, et al.
Elife
. 2022 Apr;
11.
PMID: 35416772
RIF1 is a multifunctional protein that plays key roles in the regulation of DNA processing. During repair of DNA double-strand breaks (DSBs), RIF1 functions in the 53BP1-Shieldin pathway that inhibits...
7.
Inak G, Rybak-Wolf A, Lisowski P, Pentimalli T, Juttner R, Glazar P, et al.
Nat Commun
. 2021 Mar;
12(1):1929.
PMID: 33771987
Leigh syndrome (LS) is a severe manifestation of mitochondrial disease in children and is currently incurable. The lack of effective models hampers our understanding of the mechanisms underlying the neuronal...
8.
Saha T, Sundaravinayagam D, Di Virgilio M
Trends Biochem Sci
. 2020 Nov;
46(3):184-199.
PMID: 33250286
Immunoglobulin (Ig) class switch recombination (CSR) is the process occurring in mature B cells that diversifies the effector component of antibody responses. CSR is initiated by the activity of the...
9.
Delgado-Benito V, Berruezo-Llacuna M, Altwasser R, Winkler W, Sundaravinayagam D, Balasubramanian S, et al.
J Exp Med
. 2020 Jul;
217(10).
PMID: 32609329
The establishment of protective humoral immunity is dependent on the ability of mature B cells to undergo antibody gene diversification while adjusting to the physiological stressors induced by activation with...
10.
Sundaravinayagam D, Rahjouei A, Andreani M, Tupina D, Balasubramanian S, Saha T, et al.
Cell Rep
. 2019 Aug;
28(6):1389-1399.e6.
PMID: 31390554
Class switch recombination (CSR) is a DNA recombination reaction that diversifies the effector functions of antibodies. CSR occurs via the formation and non-homologous end joining (NHEJ) repair of programmed DNA...