Judit Jane-Valbuena
Overview
Explore the profile of Judit Jane-Valbuena including associated specialties, affiliations and a list of published articles.
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26
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10996
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Recent Articles
1.
Klughammer J, Abravanel D, Segerstolpe A, Blosser T, Goltsev Y, Cui Y, et al.
Nat Med
. 2024 Oct;
30(11):3236-3249.
PMID: 39478111
Although metastatic disease is the leading cause of cancer-related deaths, its tumor microenvironment remains poorly characterized due to technical and biospecimen limitations. In this study, we assembled a multi-modal spatial...
2.
Patel A, Ashenberg O, Collins N, Segerstolpe A, Jiang S, Slyper M, et al.
bioRxiv
. 2024 Jan;
PMID: 38260392
Neuroblastoma is a pediatric cancer arising from the developing sympathoadrenal lineage with complex inter- and intra-tumoral heterogeneity. To chart this complexity, we generated a comprehensive cell atlas of 55 neuroblastoma...
3.
Zhao W, Kepecs B, Mahadevan N, Segerstolpe A, Weirather J, Besson N, et al.
bioRxiv
. 2023 Jul;
PMID: 37425718
is the most frequently mutated gene across many cancers and is associated with shorter survival in lung adenocarcinoma (LUAD). To define how mutations affect the LUAD tumor microenvironment (TME), we...
4.
Comiter C, Vaishnav E, Ciampricotti M, Li B, Yang Y, Rodig S, et al.
bioRxiv
. 2023 Mar;
PMID: 36993643
Tissue biology involves an intricate balance between cell-intrinsic processes and interactions between cells organized in specific spatial patterns, which can be respectively captured by single-cell profiling methods, such as single-cell...
5.
Keshishian H, McDonald 3rd E, Mundt F, Melanson R, Krug K, Porter D, et al.
Mol Syst Biol
. 2021 Sep;
17(9):e10156.
PMID: 34569154
Reliable methods to quantify dynamic signaling changes across diverse pathways are needed to better understand the effects of disease and drug treatment in cells and tissues but are presently lacking....
6.
Pelka K, Hofree M, Chen J, Sarkizova S, Pirl J, Jorgji V, et al.
Cell
. 2021 Aug;
184(18):4734-4752.e20.
PMID: 34450029
Immune responses to cancer are highly variable, with mismatch repair-deficient (MMRd) tumors exhibiting more anti-tumor immunity than mismatch repair-proficient (MMRp) tumors. To understand the rules governing these varied responses, we...
7.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
Nature
. 2021 Apr;
595(7865):107-113.
PMID: 33915569
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress syndrome and multiple organ failure, but little is known about its pathophysiology. Here we generated single-cell atlases of...
8.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
bioRxiv
. 2021 Mar;
PMID: 33655247
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is...
9.
Alon S, Goodwin D, Sinha A, Wassie A, Chen F, Daugharthy E, et al.
Science
. 2021 Jan;
371(6528).
PMID: 33509999
Methods for highly multiplexed RNA imaging are limited in spatial resolution and thus in their ability to localize transcripts to nanoscale and subcellular compartments. We adapt expansion microscopy, which physically...
10.
Slyper M, Porter C, Ashenberg O, Waldman J, Drokhlyansky E, Wakiro I, et al.
Nat Med
. 2020 Jun;
26(8):1307.
PMID: 32587393
An amendment to this paper has been published and can be accessed via a link at the top of the paper.