Michael Way
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Explore the profile of Michael Way including associated specialties, affiliations and a list of published articles.
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144
Citations
4273
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Recent Articles
11.
Cao L, Way M
Biochem Soc Trans
. 2024 Jan;
52(1):343-352.
PMID: 38288872
The Arp2/3 complex, which generates both branched but also linear actin filaments via activation of SPIN90, is evolutionarily conserved in eukaryotes. Several factors regulate the stability of filaments generated by...
12.
Ghasemi F, Cao L, Mladenov M, Guichard B, Way M, Jegou A, et al.
Sci Adv
. 2024 Jan;
10(4):eadj7681.
PMID: 38277459
Branched actin filaments are found in many key cellular structures. Branches are nucleated by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to the side of preexisting...
13.
Liu T, Cao L, Mladenov M, Jegou A, Way M, Moores C
Nat Struct Mol Biol
. 2024 Jan;
31(5):801-809.
PMID: 38267598
Regulation of the assembly and turnover of branched actin filament networks nucleated by the Arp2/3 complex is essential during many cellular processes, including cell migration and membrane trafficking. Cortactin is...
14.
Hernandez-Gonzalez M, Calcraft T, Nans A, Rosenthal P, Way M
mBio
. 2024 Jan;
15(2):e0313423.
PMID: 38171004
Vaccinia virus assembly in the cytoplasm of infected cells involves the formation of a biconcave viral core inside the maturing viral particle. The boundary of the core is defined by...
15.
16.
Basant A, Way M
Microbiol Spectr
. 2023 Oct;
11(6):e0152923.
PMID: 37855608
Vaccinia virus is a large double-stranded DNA virus and a close relative of Mpox and Variola virus, the causative agent of smallpox. During infection, Vaccinia hijacks its host's transport systems...
17.
18.
Sindram E, Caballero-Oteyza A, Kogata N, Chor Mei Huang S, Alizadeh Z, Gamez-Diaz L, et al.
Dis Model Mech
. 2023 Jun;
16(7).
PMID: 37382373
The Arp2/3 complex drives the formation of branched actin networks that are essential for many cellular processes. In humans, the ARPC5 subunit of the Arp2/3 complex is encoded by two...
19.
Sadhu L, Tsopoulidis N, Hasanuzzaman M, Laketa V, Way M, Fackler O
Elife
. 2023 May;
12.
PMID: 37162507
CD4 T cell activation induces nuclear and cytoplasmic actin polymerization via the Arp2/3 complex to activate cytokine expression and strengthen T cell receptor (TCR) signaling. Actin polymerization dynamics and filament...
20.
Cao L, Ghasemi F, Way M, Jegou A, Romet-Lemonne G
EMBO J
. 2023 Mar;
42(9):e113008.
PMID: 36939020
Activation of the Arp2/3 complex by VCA-motif-bearing actin nucleation-promoting factors results in the formation of "daughter" actin filaments branching off the sides of pre-existing "mother" filaments. Alternatively, when stimulated by...