Michael Thorpe
Overview
Explore the profile of Michael Thorpe including associated specialties, affiliations and a list of published articles.
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42
Citations
696
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Recent Articles
1.
Valentini P, Akula S, Alvarado-Vazquez A, Hallgren J, Fu Z, Racicot B, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338947
The extended cleavage specificities of two hematopoietic serine proteases originating from the ray-finned fish, the spotted gar (), have been characterized using substrate phage display. The preference for particular amino...
2.
Thorpe M, Akula S, Fu Z, Hellman L
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203526
The extended cleavage specificity of catfish granzyme-like II has been characterized using substrate phage display. The preference for particular amino acids at and surrounding the cleavage site was further validated...
3.
Thorpe M, Moverare R, Fischer C, Lidholm J, Rudengren M, Borres M
J Allergy Clin Immunol Pract
. 2023 May;
11(10):3021-3029.
PMID: 37245730
Allergy is defined clinically, by symptoms on allergen exposure. A patient is considered sensitized when allergen-specific IgE (sIgE) antibody can be detected in serum or plasma or a skin test...
4.
Fu Z, Akula S, Qiao C, Ryu J, Chahal G, de Garavilla L, et al.
PLoS One
. 2021 May;
16(5):e0252624.
PMID: 34048501
Ruminants have a very complex digestive system adapted for the digestion of cellulose rich food. Gene duplications have been central in the process of adapting their digestive system for this...
5.
Fu Z, Akula S, Thorpe M, Hellman L
Biol Chem
. 2021 May;
402(7):861-867.
PMID: 33977684
In order for the intestinal mucosa to absorb dietary proteins they have to be digested into single amino acids or very short peptides of a length of not more than...
6.
Berglund P, Akula S, Fu Z, Thorpe M, Hellman L
Int J Mol Sci
. 2020 Nov;
21(22).
PMID: 33198413
Serine proteases constitute the major protein content of the cytoplasmic granules of several hematopoietic cell lineages. These proteases are encoded from four different loci in mammals. One of these loci,...
7.
Akula S, Paivandy A, Fu Z, Thorpe M, Pejler G, Hellman L
Cells
. 2020 Sep;
9(9).
PMID: 32957735
Bone marrow-derived mast cells (BMMCs) are often used as a model system for studies of the role of MCs in health and disease. These cells are relatively easy to obtain...
8.
Structure-Function Relationship of Artificial Spider Silk Fibers Produced by Straining Flow Spinning
Gonska N, Lopez P, Lozano-Picazo P, Thorpe M, Guinea G, Johansson J, et al.
Biomacromolecules
. 2020 Apr;
21(6):2116-2124.
PMID: 32223220
The production of large quantities of artificial spider silk fibers that match the mechanical properties of the native material has turned out to be challenging. Recent advancements in the field...
9.
Fu Z, Akula S, Thorpe M, Hellman L
Int J Mol Sci
. 2020 Jan;
21(2).
PMID: 31963828
In two recent studies we have shown that three of the most abundant human hematopoietic serine proteases-mast cell chymase, mast cell tryptase and neutrophil cathepsin G-show a highly selective cleavage...
10.
Akula S, Paivandy A, Fu Z, Thorpe M, Pejler G, Hellman L
Cells
. 2020 Jan;
9(1).
PMID: 31947690
Mast cells (MCs) are primarily resident hematopoietic tissue cells that are localized at external and internal surfaces of the body where they act in the first line of defense. MCs...