Lars Hellman
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Explore the profile of Lars Hellman including associated specialties, affiliations and a list of published articles.
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Articles
110
Citations
1563
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Recent Articles
1.
Akula S, Alvarado-Vazquez A, Haide Mendez Enriquez E, Bal G, Franke K, Wernersson S, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684762
Quantitative transcriptomics offers a new way to obtain a detailed picture of freshly isolated cells. By direct isolation, the cells are unaffected by in vitro culture, and the isolation at...
2.
Grujic M, Alim M, Hellman L, Peterson M, Pejler G
Inflammation
. 2024 Apr;
47(5):1820-1836.
PMID: 38565760
Mast cells (MCs) are known to have a pathological impact in a variety of settings, in particular in allergic conditions. There is also limited evidence implicating MCs in diabetes, raising...
3.
Valentini P, Akula S, Alvarado-Vazquez A, Hallgren J, Fu Z, Racicot B, et al.
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38338947
The extended cleavage specificities of two hematopoietic serine proteases originating from the ray-finned fish, the spotted gar (), have been characterized using substrate phage display. The preference for particular amino...
4.
Thorpe M, Akula S, Fu Z, Hellman L
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203526
The extended cleavage specificity of catfish granzyme-like II has been characterized using substrate phage display. The preference for particular amino acids at and surrounding the cleavage site was further validated...
5.
Akula S, Tripathi S, Franke K, Wernersson S, Babina M, Hellman L
Cells
. 2024 Jan;
13(1).
PMID: 38201301
Studies of mast cell biology are dependent on relevant and validated in vitro models. Here, we present detailed information concerning the phenotype of both freshly isolated human skin mast cells...
6.
Akula S, Welinder C, Fu Z, Olsson A, Hellman L
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069163
Cows produce saliva in very large quantities to lubricate and facilitate food processing. Estimates indicate an amount of 50-150 L per day. Human saliva has previously been found to contain...
7.
Hellman L
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37833973
Macrophages are likely to be the first immune cells to have appeared during the evolution of multicellular organisms [...].
8.
Riihimaki M, Fegraeus K, Nordlund J, Waern I, Wernersson S, Akula S, et al.
Sci Rep
. 2023 Sep;
13(1):16261.
PMID: 37758813
Equine asthma (EA) is a heterogenous, complex disease, with a significant negative impact on horse welfare and performance. EA and human asthma share fundamental similarities, making EA a useful model...
9.
Aybay E, Elkhalifa M, Akula S, Wernersson S, Hellman L
Dev Comp Immunol
. 2023 Aug;
148:104920.
PMID: 37597699
Granzymes A and K are two highly homologous serine proteases expressed by mammalian cytotoxic T cells (CTLs) and natural killer (NK) cells. The locus encoding these two proteases is the...
10.
Aybay E, Ryu J, Fu Z, Akula S, Enriquez E, Hallgren J, et al.
Front Immunol
. 2023 Jul;
14:1211295.
PMID: 37497217
Granzymes A and K are two highly homologous serine proteases expressed by mammalian cytotoxic T cells (CTL) and natural killer cells (NK). Granzyme A is the most abundant of the...