Michael Stirm
Overview
Explore the profile of Michael Stirm including associated specialties, affiliations and a list of published articles.
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6
Citations
33
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Recent Articles
1.
Chirivi M, Maiullari F, Milan M, Ceraolo M, Fratini N, Fasciani A, et al.
Adv Healthc Mater
. 2025 Feb;
:e2404251.
PMID: 39962811
Advances in understanding the mechanisms behind genetic diseases like Duchenne muscular dystrophy (DMD) underscore the critical role of the extracellular matrix (ECM) composition in disease progression. Effective in vitro models...
2.
Jaudas F, Bartenschlager F, Shashikadze B, Santamaria G, Reichart D, Schnell A, et al.
Sci Transl Med
. 2025 Jan;
17(782):eadk9145.
PMID: 39841805
In patients with cystic fibrosis (CF), repeated cycles of infection and inflammation eventually lead to fatal lung damage. Although diminished mucus clearance can be restored by highly effective CFTR modulator...
3.
Laane L, Renner S, Kemter E, Stirm M, Rathkolb B, Blutke A, et al.
Pituitary
. 2024 Jul;
27(5):567-576.
PMID: 38960990
Purpose: Growth hormone (GH) is a central regulator of β-cell proliferation, insulin secretion and sensitivity. Aim of this study was to investigate the effect of GH insensitivity on pancreatic β-cell...
4.
Stirm M, Klymiuk N, Nagashima H, Kupatt C, Wolf E
Trends Mol Med
. 2024 May;
30(10):950-964.
PMID: 38749865
Duchenne muscular dystrophy (DMD) is caused by mutations in the X-linked DMD gene, resulting in the absence of dystrophin, progressive muscle degeneration, and heart failure. Genetically tailored pig models resembling...
5.
Okamoto K, Matsunari H, Nakano K, Umeyama K, Hasegawa K, Uchikura A, et al.
Regen Ther
. 2023 Sep;
24:451-458.
PMID: 37772130
Introduction: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disorder caused by mutation in the dystrophin gene () on the X chromosome. Female DMD carriers occasionally exhibit symptoms such as...
6.
Stirm M, Shashikadze B, Blutke A, Kemter E, Lange A, Stockl J, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(29):e2301250120.
PMID: 37428903
Duchenne muscular dystrophy (DMD) is a fatal X-linked disease caused by mutations in the gene, leading to complete absence of dystrophin and progressive degeneration of skeletal musculature and myocardium. In...
7.
Stirm M, Fonteyne L, Shashikadze B, Stockl J, Kurome M, Kessler B, et al.
Neuromuscul Disord
. 2022 Jun;
32(7):543-556.
PMID: 35659494
Duchenne muscular dystrophy (DMD) is a fatal X-linked disease caused by mutations in the DMD gene, leading to complete absence of dystrophin and progressive degeneration of skeletal muscles and heart....
8.
Stirm M, Fonteyne L, Shashikadze B, Lindner M, Chirivi M, Lange A, et al.
Dis Model Mech
. 2021 Nov;
14(12).
PMID: 34796900
Large-animal models for Duchenne muscular dystrophy (DMD) are crucial for the evaluation of diagnostic procedures and treatment strategies. Pigs cloned from male cells lacking DMD exon 52 (DMDΔ52) exhibit molecular,...