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Michael Schemann

Explore the profile of Michael Schemann including associated specialties, affiliations and a list of published articles. Areas
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Articles 96
Citations 2696
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Recent Articles
1.
Vignali S, Buhner S, Greiter W, Daniel H, Frieling T, Schemann M, et al.
Front Neurosci . 2024 Jul; 18:1291554. PMID: 39015376
Introduction: We previously showed enteric nerve activation after application of colonic mucosal biopsy supernatants from patients with irritable bowel syndrome (IBS). The question remains whether this is a region-specific or...
2.
Allam S, Kruger D, Michel K, Schnabl K, Klingenspor M, Schemann M, et al.
Neurogastroenterol Motil . 2024 Feb; 36(10):e14761. PMID: 38342975
Introduction: The herbal preparation STW 5 ameliorates functional dyspepsia partly by relaxing smooth muscle of the proximal stomach, thus improving gastric accommodation. We explored the unknown pathways responsible for this...
3.
Elfers K, Schauffele S, Hoppe S, Michel K, Zeller F, Demir I, et al.
PLoS One . 2023 Apr; 18(4):e0282732. PMID: 37053302
It was suggested that intestinal mucosal secretion is enhanced during muscle relaxation and contraction. Mechanisms of mechanically induced secretion have been studied in rodent species. We used voltage clamp Ussing...
4.
Buhner S, Schauffele S, Giesbertz P, Demir I, Zeller F, Traidl-Hoffmann C, et al.
Neurogastroenterol Motil . 2023 Mar; 35(7):e14559. PMID: 36989179
Background: Non-allergenic, low molecular weight components of pollen grains are suspected to trigger changes in gut functions, sometimes leading to inflammatory conditions. Based on extensive neuroimmune communication in the gut...
5.
Kohl T, Ridzal L, Kuch B, Hartel M, Kreft C, Musoski A, et al.
Front Zool . 2023 Feb; 20(1):8. PMID: 36759847
Background: Gastrointestinal (GI) functions are controlled by the enteric nervous system (ENS) in vertebrates, but data on snakes are scarce, as most studies were done in mammals. However, the feeding...
6.
Jooss T, Zhang J, Zimmer B, Rezzonico-Jost T, Rissiek B, Felipe Pelczar P, et al.
Mucosal Immunol . 2023 Jan; 16(2):180-193. PMID: 36634819
The blockade or deletion of the pro-inflammatory P2X7 receptor channel has been shown to reduce tissue damage and symptoms in models of inflammatory bowel disease, and P2X7 receptors on enteric...
7.
Annahazi A, Schemann M
Adv Exp Med Biol . 2022 Dec; 1383:1-8. PMID: 36587141
Anti-neuronal autoantibodies can lead to subacute gastrointestinal dysmotility, presenting with various symptoms typical of intestinal pseudoobstruction, achalasia, gastroparesis, or slow intestinal transit, among others. Such autoantibodies may be produced in...
8.
Michel K, Kuch B, Dengler S, Demir I, Zeller F, Schemann M
Neurogastroenterol Motil . 2022 Aug; 34(12):e14440. PMID: 35929768
Background: Despite numerous studies on the enteric nervous system (ENS), we lack fundamental knowledge on neuronal densities or total neuron numbers in different species. There are more anecdotal than actual...
9.
Jooss T, Kuch B, Zhang J, Schemann M, Nicke A
Methods Mol Biol . 2022 Jul; 2510:145-156. PMID: 35776324
P2X7 receptors play an important role in cytokine release and immune cell regulation. Their upregulation has been described in inflammatory and degenerative processes and P2X7 blockade or deletion has been...
10.
Annahazi A, Berger T, Demir I, Zeller F, Muller M, Anneser M, et al.
Neurogastroenterol Motil . 2022 Apr; 34(10):e14380. PMID: 35438222
Background: Serotonin (5-HT) is an important mediator in the gastrointestinal tract, acting on different neuronal 5-HT receptors. The ionotropic 5-HT receptor mediates immediate but transient spike discharge in human enteric...