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Klaus Michel

Explore the profile of Klaus Michel including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 704
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Recent Articles
1.
Allam S, Kruger D, Michel K, Schnabl K, Klingenspor M, Schemann M, et al.
Neurogastroenterol Motil . 2024 Feb; 36(10):e14761. PMID: 38342975
Introduction: The herbal preparation STW 5 ameliorates functional dyspepsia partly by relaxing smooth muscle of the proximal stomach, thus improving gastric accommodation. We explored the unknown pathways responsible for this...
2.
Elfers K, Schauffele S, Hoppe S, Michel K, Zeller F, Demir I, et al.
PLoS One . 2023 Apr; 18(4):e0282732. PMID: 37053302
It was suggested that intestinal mucosal secretion is enhanced during muscle relaxation and contraction. Mechanisms of mechanically induced secretion have been studied in rodent species. We used voltage clamp Ussing...
3.
Kohl T, Ridzal L, Kuch B, Hartel M, Kreft C, Musoski A, et al.
Front Zool . 2023 Feb; 20(1):8. PMID: 36759847
Background: Gastrointestinal (GI) functions are controlled by the enteric nervous system (ENS) in vertebrates, but data on snakes are scarce, as most studies were done in mammals. However, the feeding...
4.
Michel K, Kuch B, Dengler S, Demir I, Zeller F, Schemann M
Neurogastroenterol Motil . 2022 Aug; 34(12):e14440. PMID: 35929768
Background: Despite numerous studies on the enteric nervous system (ENS), we lack fundamental knowledge on neuronal densities or total neuron numbers in different species. There are more anecdotal than actual...
5.
Annahazi A, Berger T, Demir I, Zeller F, Muller M, Anneser M, et al.
Neurogastroenterol Motil . 2022 Apr; 34(10):e14380. PMID: 35438222
Background: Serotonin (5-HT) is an important mediator in the gastrointestinal tract, acting on different neuronal 5-HT receptors. The ionotropic 5-HT receptor mediates immediate but transient spike discharge in human enteric...
6.
Michel K, Kruger D, Schauffele S, Zeller F, Demir I, Theisen J, et al.
Neurogastroenterol Motil . 2021 May; 33(8):e14164. PMID: 33960578
Background: Acetylcholine is the main excitatory neurotransmitter in the enteric nervous system (ENS) in all animal models examined so far. However, data for the human ENS is scarce. Methods: We...
7.
Filzmayer A, Elfers K, Michel K, Buhner S, Zeller F, Demir I, et al.
Sci Rep . 2020 Aug; 10(1):13791. PMID: 32796868
The pig is commonly believed to be a relevant model for human gut functions-however, there are only a few comparative studies and none on neural control mechanisms. To address this...
8.
Krueger D, Schauffele S, Zeller F, Demir I, Theisen J, Michel K, et al.
Neurogastroenterol Motil . 2019 Oct; 32(2):e13748. PMID: 31612595
Background: Herbal medicinal products with a broad activity spectrum may be promising alternatives to treat functional gastrointestinal disorders (FGD). Menthacarin is a drug with a fixed combination of peppermint and...
9.
Kugler E, Michel K, Kirchenbuchler D, Dreissen G, Csiszar A, Merkel R, et al.
Neuroscience . 2018 Jan; 372:213-224. PMID: 29317262
Within the enteric nervous system, the neurons in charge to control motility of the gastrointestinal tract reside in a particular location nestled between two perpendicular muscle layers which contract and...
10.
Li Q, Michel K, Annahazi A, Demir I, Ceyhan G, Zeller F, et al.
Sci Rep . 2016 Dec; 6:38216. PMID: 27905561
IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneoplastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung carcinoma. We show here that...