Michael P Walsh
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Explore the profile of Michael P Walsh including associated specialties, affiliations and a list of published articles.
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139
Citations
4070
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Recent Articles
1.
Umeda M, Hiltenbrand R, Michmerhuizen N, Barajas J, Thomas M, Arthur B, et al.
medRxiv
. 2025 Feb;
PMID: 39974131
Leukemias with rearrangements exhibit heterogeneous phenotypes correlated to fusion partners, whereas the mechanism responsible for this heterogeneity is poorly understood. Through genome-wide mutational and transcriptional analyses of 177 -rearranged leukemias,...
2.
Thomas 3rd M, Qi W, Walsh M, Ma J, Westover T, Abdelhamed S, et al.
Leukemia
. 2024 Mar;
38(5):991-1002.
PMID: 38454121
MGA (Max-gene associated) is a dual-specificity transcription factor that negatively regulates MYC-target genes to inhibit proliferation and promote differentiation. Loss-of-function mutations in MGA have been commonly identified in several hematological...
3.
Barajas J, Umeda M, Contreras L, Khanlari M, Westover T, Walsh M, et al.
Haematologica
. 2024 Mar;
109(8):2459-2468.
PMID: 38426285
Recent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (UBTF). These alterations, which account...
4.
Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek J, et al.
Nat Genet
. 2024 Jan;
56(2):281-293.
PMID: 38212634
Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific driver alterations, many of which are underrepresented in the current classification schemas. To comprehensively define the genomic landscape of...
5.
Barajas J, Umeda M, Contreras L, Khanlari M, Westover T, Walsh M, et al.
medRxiv
. 2023 Nov;
PMID: 38014207
Recent genomic studies in adult and pediatric acute myeloid leukemia (AML) demonstrated recurrent in-frame tandem duplications (TD) in exon 13 of upstream binding transcription factor (). These alterations, which account...
6.
Barajas J, Rasouli M, Umeda M, Hiltenbrand R, Abdelhamed S, Mohnani R, et al.
Blood
. 2023 Oct;
143(7):619-630.
PMID: 37890156
UBTF tandem duplications (UBTF-TDs) have recently emerged as a recurrent alteration in pediatric and adult acute myeloid leukemia (AML). UBTF-TD leukemias are characterized by a poor response to conventional chemotherapy...
7.
Sutula M, Christen I, Bersin E, Walsh M, Chen K, Mallek J, et al.
Nat Mater
. 2023 Aug;
22(11):1338-1344.
PMID: 37604910
Solid-state quantum emitters have emerged as a leading quantum memory for quantum networking applications. However, standard optical characterization techniques are neither efficient nor repeatable at scale. Here we introduce and...
8.
Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek J, et al.
Res Sq
. 2023 Jul;
PMID: 37398194
Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific driver alterations, many of which are underrepresented in the current classification schemas. To comprehensively define the genomic landscape of...
9.
Liu Y, Klein J, Bajpai R, Dong L, Tran Q, Kolekar P, et al.
Nat Commun
. 2023 Apr;
14(1):1739.
PMID: 37019972
Oncogenic fusions formed through chromosomal rearrangements are hallmarks of childhood cancer that define cancer subtype, predict outcome, persist through treatment, and can be ideal therapeutic targets. However, mechanistic understanding of...
10.
Abdelhamed S, Thomas 3rd M, Westover T, Umeda M, Xiong E, Rolle C, et al.
J Clin Invest
. 2022 Sep;
132(21).
PMID: 36074606
SAMD9 and SAMD9L germline mutations have recently emerged as a new class of predispositions to pediatric myeloid neoplasms. Patients commonly have impaired hematopoiesis, hypocellular marrows, and a greater risk of...