Michael N T Souter
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Explore the profile of Michael N T Souter including associated specialties, affiliations and a list of published articles.
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12
Citations
146
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Recent Articles
1.
Wang H, Souter M, de Lima Moreira M, Li S, Zhou Y, Nelson A, et al.
Sci Immunol
. 2024 Dec;
9(102):eadp9841.
PMID: 39642244
Mucosal-associated invariant T (MAIT) cells are known for their rapid effector functions and antibacterial immune protection. Here, we define the plasticity of interferon-γ (IFN-γ)-producing MAIT1 and interleukin-17A (IL-17A)-producing MAIT17 cell...
2.
McInerney M, Awad W, Souter M, Kang Y, Wang C, Chan Yew Poa K, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(49):e2414792121.
PMID: 39589872
The major histocompatibility complex class I related protein (MR1) presents microbially derived vitamin B2 precursors to mucosal-associated invariant T (MAIT) cells. MR1 can also present other metabolites to activate MR1-restricted...
3.
Nelson A, Wang H, Dewar P, Eddy E, Li S, Lim X, et al.
Front Immunol
. 2023 Sep;
14:1109759.
PMID: 37720229
Introduction: Mucosal-associated invariant T (MAIT) cells are a population of innate-like T cells, which mediate host immunity to microbial infection by recognizing metabolite antigens derived from microbial riboflavin synthesis presented...
4.
Patton T, Zhao Z, Lim X, Eddy E, Wang H, Nelson A, et al.
Cell Death Dis
. 2023 Feb;
14(2):111.
PMID: 36774342
Cell death mechanisms in T lymphocytes vary according to their developmental stage, cell subset and activation status. The cell death control mechanisms of mucosal-associated invariant T (MAIT) cells, a specialized...
5.
Souter M, Awad W, Li S, Pediongco T, Meehan B, Meehan L, et al.
J Exp Med
. 2022 Aug;
219(9).
PMID: 36018322
Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of riboflavin-based antigens presented by the major histocompatibility complex class I (MHC-I)-related protein 1 (MR1). Most MAIT cells in human...
6.
Boonpattanaporn N, Kongkaew T, Sengprasert P, Souter M, Lakananurak N, Rerknimitr R, et al.
J Leukoc Biol
. 2022 Jun;
112(4):717-732.
PMID: 35704477
Mucosal-associated invariant T (MAIT) cells are innate-like, unconventional T cells that are present in peripheral blood and mucosal surfaces. A clear understanding of how MAIT cells in the mucosae function...
7.
Souter M, Eckle S
Front Immunol
. 2020 Oct;
11:1845.
PMID: 33013835
Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that recognize the evolutionarily conserved major histocompatibility complex (MHC) class I-like antigen-presenting molecule known as MHC class I...
8.
de Lima Moreira M, Souter M, Chen Z, Loh L, McCluskey J, Pellicci D, et al.
Allergy
. 2020 Mar;
75(10):2477-2490.
PMID: 32181878
Conventional T cells recognise protein-derived antigens in the context of major histocompatibility complex (MHC) class Ia and class II molecules and provide anti-microbial and anti-tumour immunity. Conventional T cells have...
9.
Le Nours J, Gherardin N, Ramarathinam S, Awad W, Wiede F, Gully B, et al.
Science
. 2019 Dec;
366(6472):1522-1527.
PMID: 31857486
T cell receptors (TCRs) recognize antigens presented by major histocompatibility complex (MHC) and MHC class I-like molecules. We describe a diverse population of human γδ T cells isolated from peripheral...
10.
Souter M, Loh L, Li S, Meehan B, Gherardin N, Godfrey D, et al.
Curr Protoc Immunol
. 2019 Nov;
127(1):e90.
PMID: 31763790
Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells restricted by the major histocompatibility complex (MHC) class I-like molecule MHC-related protein 1 (MR1). MAIT cells are found...