Michael Lutteropp
Overview
Explore the profile of Michael Lutteropp including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
1250
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0
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Recent Articles
1.
Zhou D, Kischel R, Stienen S, Townsley D, Sternjak A, Lutteropp M, et al.
Clin Pharmacol Ther
. 2024 Sep;
117(1):225-231.
PMID: 39285508
Bispecific T-cell engagers (Bi-TCEs) have revolutionized the treatment and management of both hematological and solid tumor indications with opportunities to become best-in-class therapeutics for cancer. However, defining the dose and...
2.
Pham E, Friedrich M, Aeffner F, Lutteropp M, Mariano N, Deegen P, et al.
Mol Cancer Ther
. 2021 Aug;
20(10):1977-1987.
PMID: 34376583
MUC12 is a transmembrane mucin that is highly expressed in >50% of primary and metastatic colorectal tumors. MUC12 is also expressed by normal epithelial cells of the colon and small...
3.
Jitschin R, Saul D, Braun M, Tohumeken S, Volkl S, Kischel R, et al.
J Immunother Cancer
. 2018 Nov;
6(1):116.
PMID: 30396365
Acute myeloid leukemia (AML) is the most common acute leukemia amongst adults with a 5-year overall survival lower than 30%. Emerging evidence suggest that immune alterations favor leukemogenesis and/or AML...
4.
Stamm H, Klingler F, Grossjohann E, Muschhammer J, Vettorazzi E, Heuser M, et al.
Oncogene
. 2018 Jun;
37(39):5269-5280.
PMID: 29855615
Immune checkpoints are promising targets in cancer therapy. Recently, poliovirus receptor (PVR) and poliovirus receptor-related 2 (PVRL2) have been identified as novel immune checkpoints. In this investigation we show that...
5.
Luis T, Luc S, Mizukami T, Boukarabila H, Thongjuea S, Woll P, et al.
Nat Immunol
. 2016 Oct;
17(12):1424-1435.
PMID: 27695000
The final stages of restriction to the T cell lineage occur in the thymus after the entry of thymus-seeding progenitors (TSPs). The identity and lineage potential of TSPs remains unclear....
6.
Drissen R, Buza-Vidas N, Woll P, Thongjuea S, Gambardella A, Giustacchini A, et al.
Nat Immunol
. 2016 Apr;
17(6):666-676.
PMID: 27043410
According to current models of hematopoiesis, lymphoid-primed multi-potent progenitors (LMPPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs) (Lin(-)Sca-1(+)c-Kit(+)CD34(+)CD41(hi)) establish an early branch point for separate lineage-commitment pathways from hematopoietic stem cells,...
7.
Boiers C, Carrelha J, Lutteropp M, Luc S, Green J, Azzoni E, et al.
Cell Stem Cell
. 2013 Sep;
13(5):535-48.
PMID: 24054998
In jawed vertebrates, development of an adaptive immune-system is essential for protection of the born organism against otherwise life-threatening pathogens. Myeloid cells of the innate immune system are formed early...
8.
Sanjuan-Pla A, Macaulay I, Jensen C, Woll P, Luis T, Mead A, et al.
Nature
. 2013 Aug;
502(7470):232-6.
PMID: 23934107
The blood system is maintained by a small pool of haematopoietic stem cells (HSCs), which are required and sufficient for replenishing all human blood cell lineages at millions of cells...
9.
Mead A, Kharazi S, Atkinson D, Macaulay I, Pecquet C, Loughran S, et al.
Cell Rep
. 2013 Jun;
3(6):1766-76.
PMID: 23727242
Whether signals mediated via growth factor receptors (GFRs) might influence lineage fate in multipotent progenitors (MPPs) is unclear. We explored this issue in a mouse knockin model of gain-of-function Flt3-ITD...
10.
Buza-Vidas N, Cismasiu V, Moore S, Mead A, Woll P, Lutteropp M, et al.
Blood
. 2012 Aug;
120(12):2412-6.
PMID: 22869792
MicroRNAs (miRs) are involved in many aspects of normal and malignant hematopoiesis, including hematopoietic stem cell (HSC) self-renewal, proliferation, and terminal differentiation. However, a role for miRs in the generation...