Tiago C Luis
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Explore the profile of Tiago C Luis including associated specialties, affiliations and a list of published articles.
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27
Citations
1779
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Recent Articles
1.
Cheong S, Luis T, Hind M, Dean C
Bio Protoc
. 2024 Apr;
14(8):e4980.
PMID: 38686349
Precision-cut lung slices (PCLS), ex vivo 3D lung tissue models, have been widely used for various applications in lung research. PCLS serve as an excellent intermediary between in vitro and...
2.
Cheong S, Luis T, Stewart M, Hillier R, Hind M, Dean C
Dis Model Mech
. 2023 Oct;
16(11).
PMID: 37828896
Precision-cut lung slices (PCLS) are used for a variety of applications. However, methods to manipulate genes in PCLS are currently limited. We developed a new method, TAT-Cre recombinase-mediated floxed allele...
3.
Luis T, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, et al.
Nat Commun
. 2023 Sep;
14(1):6062.
PMID: 37770432
Hematopoietic stem cells (HSCs) residing in specialized niches in the bone marrow are responsible for the balanced output of multiple short-lived blood cell lineages in steady-state and in response to...
4.
Jackson W, Giacomassi C, Ward S, Owen A, Luis T, Spear S, et al.
Elife
. 2023 Aug;
12.
PMID: 37566453
Monocytes are heterogeneous innate effector leukocytes generated in the bone marrow and released into circulation in a CCR2-dependent manner. During infection or inflammation, myelopoiesis is modulated to rapidly meet the...
5.
Matsuoka S, Facchini R, Luis T, Carrelha J, Woll P, Mizukami T, et al.
Blood
. 2023 Aug;
142(19):1622-1632.
PMID: 37562000
A critical regulatory role of hematopoietic stem cell (HSC) vascular niches in the bone marrow has been implicated to occur through endothelial niche cell expression of KIT ligand. However, endothelial-derived...
6.
7.
Haltalli M, Watcham S, Wilson N, Eilers K, Lipien A, Ang H, et al.
Nat Cell Biol
. 2020 Nov;
22(12):1399-1410.
PMID: 33230302
Severe infections are a major stress on haematopoiesis, where the consequences for haematopoietic stem cells (HSCs) have only recently started to emerge. HSC function critically depends on the integrity of...
8.
Carrelha J, Lin D, Rodriguez-Fraticelli A, Luis T, Wilkinson A, Cabezas-Wallscheid N, et al.
Exp Hematol
. 2020 Aug;
89:26-36.
PMID: 32735908
The coordinated differentiation of hematopoietic stem and progenitor cells (HSPCs) into the various mature blood cell types is responsible for sustaining blood and immune system homeostasis. The cell fate decisions...
9.
Luis T, Lawson H, Kranc K
Cell Stem Cell
. 2020 Mar;
26(3):299-301.
PMID: 32142657
Hematopoietic stem cells (HSCs) remain quiescent to preserve long-term integrity. In this issue of Cell Stem Cell, Hinge et al. (2020) and Liang et al. (2020) demonstrate that HSCs achieve...
10.
Luis T, Wilkinson A, Beerman I, Jaiswal S, Shlush L
Exp Hematol
. 2019 Sep;
77:1-5.
PMID: 31472170
Adult hematological malignancies, such as acute myeloid leukemia, are thought to arise through the gradual acquisition of oncogenic mutations within long-lived hematopoietic stem cells (HSCs). Genomic analysis of peripheral blood...