Michael Lardelli
Overview
Explore the profile of Michael Lardelli including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
76
Citations
1002
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Barthelson K, Protzman R, Snel M, Hemsley K, Lardelli M
Biochim Biophys Acta Mol Basis Dis
. 2025 Jan;
1871(3):167651.
PMID: 39798820
Sanfilippo syndrome (mucopolysaccharidosis type III, MPSIII) causes childhood dementia, while Alzheimer's disease is the most common type of adult-onset dementia. There is no cure for either of these diseases, and...
2.
Hillman C, Fontana B, Amstislavskaya T, Gorbunova M, Altenhofen S, Barthelson K, et al.
Res Sq
. 2024 Nov;
PMID: 39483890
The reproducibility crisis in bioscience, characterized by inconsistent study results, impedes our understanding of biological processes and global collaborative studies offer a unique solution. This study is the first global...
3.
Baer L, Barthelson K, Postlethwait J, Adelson D, Pederson S, Lardelli M
PLoS Comput Biol
. 2024 Feb;
20(2):e1011868.
PMID: 38346074
In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted...
4.
Lardelli M, Baer L, Hin N, Allen A, Pederson S, Barthelson K
J Alzheimers Dis
. 2023 Sep;
99(s2):S367-S381.
PMID: 37742650
The degree to which non-human animals can be used to model Alzheimer's disease is a contentious issue, particularly as there is still widespread disagreement regarding the pathogenesis of this neurodegenerative...
5.
Lardelli M
J Alzheimers Dis
. 2023 Sep;
96(1):13-39.
PMID: 37718800
Probabilistic and parsimony-based arguments regarding available genetics data are used to propose that Hardy and Higgin's amyloid cascade hypothesis is valid but is commonly interpreted too narrowly to support, incorrectly,...
6.
Ha T, Burgess R, Newman M, Moey C, Mandelstam S, Gardner A, et al.
Genes (Basel)
. 2023 Aug;
14(8).
PMID: 37628618
Aicardi Syndrome (AIC) is a rare neurodevelopmental disorder recognized by the classical triad of agenesis of the corpus callosum, chorioretinal lacunae and infantile epileptic spasms syndrome. The diagnostic criteria of...
7.
Allen A, Barthelson K, Lardelli M
Biol Methods Protoc
. 2023 Aug;
8(1):bpad015.
PMID: 37547169
DNA size markers (also known as 'molecular weight markers' or 'DNA ladders') are an essential tool when using gel electrophoresis to identify and purify nucleic acids. However, the cost of...
8.
Baer L, Barthelson K, Postlethwait J, Adelson D, Pederson S, Lardelli M
bioRxiv
. 2023 Mar;
PMID: 36945478
In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted...
9.
Jayne T, Newman M, Baer L, Lardelli M
BMC Res Notes
. 2021 Dec;
14(1):460.
PMID: 34930423
Objective: NGFR/p75NTR and NRADD/NRH proteins are closely related structurally and are encoded by genes that arose from a duplication event early in vertebrate evolution. The transmembrane domain (TMD) of NGFR...
10.
Barthelson K, Newman M, Lardelli M
Dis Model Mech
. 2021 Nov;
15(1).
PMID: 34842276
Energy production is the most fundamentally important cellular activity supporting all other functions, particularly in highly active organs, such as brains. Here, we summarise transcriptome analyses of young adult (pre-disease)...