Michael L Pendrak
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Explore the profile of Michael L Pendrak including associated specialties, affiliations and a list of published articles.
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19
Citations
797
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Recent Articles
1.
Pendrak M, Roberts D
PLoS One
. 2015 Jun;
10(6):e0126919.
PMID: 26039220
Transitions between yeast and hyphae are essential for Candida albicans pathogenesis. The genetic programs that regulate its hyphal development can be distinguished by embedded versus aerobic surface agar invasion. Hbr1,...
2.
Kaur S, Chang T, Singh S, Lim L, Mannan P, Garfield S, et al.
J Immunol
. 2014 Sep;
193(8):3914-24.
PMID: 25200950
Thrombospondin-1 (TSP1) inhibits angiogenesis, in part, by interacting with the ubiquitous cell-surface receptor CD47. In endothelial cells, CD47 interacts directly with vascular endothelial growth factor receptor (VEGFR)-2, and TSP1 inhibits...
3.
Kaur S, Soto-Pantoja D, Stein E, Liu C, Elkahloun A, Pendrak M, et al.
Sci Rep
. 2013 Apr;
3:1673.
PMID: 23591719
Signaling through the thrombospondin-1 receptor CD47 broadly limits cell and tissue survival of stress, but the molecular mechanisms are incompletely understood. We now show that loss of CD47 permits sustained...
4.
Soto-Pantoja D, Miller T, Pendrak M, DeGraff W, Sullivan C, Ridnour L, et al.
Autophagy
. 2012 Aug;
8(11):1628-42.
PMID: 22874555
Accidental or therapeutic exposure to ionizing radiation has severe physiological consequences and can result in cell death. We previously demonstrated that deficiency or blockade of the ubiquitously expressed receptor CD47...
5.
Englund E, Wang D, Fujigaki H, Sakai H, Micklitsch C, Ghirlando R, et al.
Nat Commun
. 2012 Jan;
3:614.
PMID: 22233624
Multivalent effects dictate the binding affinity of multiple ligands on one molecular entity to receptors. Integrins are receptors that mediate cell attachment through multivalent binding to peptide sequences within the...
6.
Pendrak M, Roberts D
RNA
. 2011 Oct;
17(12):2235-48.
PMID: 22028364
Ribosome assembly begins with conversion of a polycistronic precursor into 18S, 5.8S, and 25S rRNAs. In the ascomycete fungus Candida albicans, rRNA transcription starts 604 nt upstream of the 18S...
7.
Peterson A, Pendrak M, Roberts D
J Biol Chem
. 2011 Mar;
286(16):13914-24.
PMID: 21372131
HBR1 (hemoglobin response gene 1) is an essential gene in Candida albicans that positively regulates mating type locus MTLα gene expression and thereby regulates cell type-specific developmental genes. Hbr1p contains...
8.
Kaur S, Kuznetsova S, Pendrak M, Sipes J, Romeo M, Li Z, et al.
J Biol Chem
. 2011 Feb;
286(17):14991-5002.
PMID: 21343308
Cell surface proteoglycans on T cells contribute to retroviral infection, binding of chemokines and other proteins, and are necessary for some T cell responses to the matricellular glycoprotein thrombospondin-1. The...
9.
Kaur S, Martin-Manso G, Pendrak M, Garfield S, Isenberg J, Roberts D
J Biol Chem
. 2010 Oct;
285(50):38923-32.
PMID: 20923780
Thrombospondin-1 (TSP1) can inhibit angiogenic responses directly by interacting with VEGF and indirectly by engaging several endothelial cell TSP1 receptors. We now describe a more potent mechanism by which TSP1...
10.
Ptaszynska M, Pendrak M, Stracke M, Roberts D
Mol Cancer Res
. 2010 Mar;
8(3):309-21.
PMID: 20197381
Important roles for vascular endothelial growth factor (VEGF) and autotaxin (ATX) have been established for embryonic vasculogenesis and cancer progression. We examined whether these two angiogenic factors cooperate in regulation...