David D Roberts
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Explore the profile of David D Roberts including associated specialties, affiliations and a list of published articles.
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164
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11466
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Recent Articles
1.
Dong K, Nihal R, Meyer T, Singh S, Kaur S, Roberts D
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201643
An association between high CD47 expression and poor cancer survival has been attributed to its function on malignant cells to inhibit phagocytic clearance. However, CD47 mRNA expression in some cancers...
2.
Banerjee R, Meyer T, Cam M, Kaur S, Roberts D
Elife
. 2024 Jul;
12.
PMID: 38979889
Extramedullary erythropoiesis is not expected in healthy adult mice, but erythropoietic gene expression was elevated in lineage-depleted spleen cells from mice. Expression of several genes associated with early stages of...
3.
Petersen J, Mekhedov E, Kaur S, Roberts D, Zimmerberg J
J Extracell Biol
. 2024 Jun;
2(4):e79.
PMID: 38939691
Extracellular vesicles (EVs) released by endothelial cells support vascular homeostasis. To better understand endothelial cell EV biogenesis, we examined cultured human umbilical vein endothelial cells (HUVECs) prepared by rapid freezing,...
4.
Kaur S, Reginauld B, Razjooyan S, Phi T, Singh S, Meyer T, et al.
Front Cell Dev Biol
. 2024 Mar;
12:1356421.
PMID: 38495618
Signal regulatory protein-α (SIRPα, SHPS-1, CD172a) expressed on myeloid cells transmits inhibitory signals when it engages its counter-receptor CD47 on an adjacent cell. Elevated CD47 expression on some cancer cells...
5.
Banerjee R, Meyer T, Cam M, Kaur S, Roberts D
bioRxiv
. 2023 Oct;
PMID: 37808833
Extramedullary erythropoiesis is not expected in healthy adult mice, but erythropoietic gene expression was elevated in lineage-depleted spleen cells from mice. Expression of several genes associated with early stages of...
6.
Kaur S, Roberts D
Semin Cell Dev Biol
. 2023 May;
155(Pt B):22-31.
PMID: 37258315
Thrombospondin-1 is a secreted matricellular glycoprotein that modulates cell behavior by interacting with components of the extracellular matrix and with several cell surface receptors. Its presence in the extracellular matrix...
7.
Kaur S, Awad D, Finney R, Meyer T, Singh S, Cam M, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768931
Elevated expression of CD47 in some cancers is associated with poor survival related to its function as an innate immune checkpoint when expressed on tumor cells. In contrast, elevated CD47...
8.
Kaur S, Roberts D
J Cell Commun Signal
. 2023 Jan;
17(3):485-493.
PMID: 36689135
Matricellular proteins comprise several families of secreted proteins that function in higher animals at the interface between cells and their surrounding extracellular matrix. Targeted gene disruptions that result in loss...
9.
Bronson S, Westwood B, Cook K, Emenaker N, Chappell M, Roberts D, et al.
Metabolites
. 2022 Nov;
12(11).
PMID: 36355119
Thrombospondin-1 (TSP1) is a matricellular protein with many important roles in mediating carcinogenesis, fibrosis, leukocyte recruitment, and metabolism. We have previously shown a role of diet in the absence of...
10.
Kaur S, Livak F, Daaboul G, Anderson L, Roberts D
J Extracell Vesicles
. 2022 Sep;
11(9):e12265.
PMID: 36107309
CD47 regulates the trafficking of specific coding and noncoding RNAs into extracellular vesicles (EVs), and the RNA contents of CD47 EVs differ from that of CD63 EVs released by the...